Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2021 Feb 24:14:527-536.
doi: 10.2147/JPR.S289018. eCollection 2021.

Effects of Different Local Analgesic Techniques on Postoperative Quality of Life and Pain in Patients Undergoing Total Hip Arthroplasty Under General Anesthesia: A Randomized Controlled Trial

Rui Yang  1 , Rui-Hong Liu  1 , Jia-Nan Xu  1 , Guang-Hong Xu  1   2 , Xiao-Bin Jin  1 , Rui Xiao  1 , Bin Mei  1
Affiliations
Clinical Trial

Effects of Different Local Analgesic Techniques on Postoperative Quality of Life and Pain in Patients Undergoing Total Hip Arthroplasty Under General Anesthesia: A Randomized Controlled Trial

Rui Yang et al. J Pain Res. .

Abstract

Background: Both lumbosacral plexus block (LSPB) and local infiltration analgesia (LIA) can provide postoperative analgesia for patients undergoing total hip arthroplasty (THA). The current study aimed to compare the differences between LSPB and LIA on postoperative pain and quality of life (QoL) in THA patients.

Methods: A total of 117 patients aged 40-80 years, ASA I-III, were prospectively randomized into two groups: a general anesthesia plus LSPB (Group LSPB) and a general anesthesia plus LIA (Group LIA). Pain intensity and opioid consumption were recorded Within 72 hours after surgery. QoL was measured by EQ-5D and EQ-VAS questionnaires, and the incidence of postoperative pain was measured as part of the EQ-5D on day 1, day 3, day 7, and month 1, month 3, and month 6 after surgery.

Results: EQ-5D scores: Mobility, Self-Care, Usual Activities, Pain/Discomfort, and Anxiety/Depression were higher in Group LSPB versus Group LIA throughout six-month follow-ups (p = 0.039). The pain intensity was lower in Group LSPB than in Group LIA 0-12 h after surgery (2.41 vs 2.79, p = 0.01), but was higher in Group LSPB than in Group LIA 12-24 h (2.59 vs 2.05, p = 0.02) and 24-48 h (2.18 vs 1.73, p = 0.02) after surgery. There were no differences in opioid consumption between the groups during the first 72 postoperative hours. In the first month after surgery, more patients in Group LSPB than in Group LIA had no pain (52 vs 40, p = 0.04).

Conclusion: Both LSPB and LIA can provide satisfactory postoperative analgesia. The LSPB is better than LIA for long-term QoL in THA patients undergoing general anesthesia.

Clinical trial registration number: The Chinese Clinical Trial Registry (ChiCTR-INR-17012545).

Keywords: local infiltration analgesia; lumbosacral plexus block; postoperative pain; quality of life; total hip arthroplasty.

PubMed Disclaimer

Conflict of interest statement

None of the authors have any conflicts of interest.

Figures

Figure 1
Figure 1
The CONSORT flowchart.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Koutras C, Antoniou SA, Talias MA, et al. Impact of total hip resurfacing arthroplasty on health-related quality of life measures: a systematic review and meta-analysis. J Arthroplasty. 2015;30(11):1938–1952. doi:10.1016/j.arth.2015.05.014 - DOI - PubMed
    1. Sloan M, Premkumar A, Sheth NP. Projected volume of primary total joint arthroplasty in the U.S. 2014 to 2030. J Bone Joint Surg Am. 2018;100(17):1455–1460. doi:10.2106/JBJS.17.01617 - DOI - PubMed
    1. de Visme V, Picart F, Le Jouan R, et al. Combined lumbar and sacral plexus block compared with plain bupivacaine spinal anesthesia for hip fractures in the elderly. Reg Anesth Pain Med. 2000;25(2):158–162. doi:10.1097/00115550-200003000-00005 - DOI - PubMed
    1. Guay J, Parker MJ, Griffiths R, et al. Peripheral nerve blocks for hip fractures: a cochrane review. Anesth Analg. 2018;126(5):1695–1704. doi:10.1213/ANE.0000000000002489 - DOI - PubMed
    1. Gadsden JC, Lindenmuth DM, Hadzic A, et al. Lumbar plexus block using high-pressure injection leads to contralateral and epidural spread. Anesthesiology. 2008;109(4):683–688. doi:10.1097/ALN.0b013e31818631a7 - DOI - PubMed

LinkOut - more resources