Effects of a protease inhibitor on biosynthesis of Escherichia coli proteins
- PMID: 336598
 - PMCID: PMC235604
 - DOI: 10.1128/jb.132.3.1021-1023.1977
 
Effects of a protease inhibitor on biosynthesis of Escherichia coli proteins
Abstract
A protease inhibitor, tosyl-L-lysine chloromethylketone, altered the composition of newly synthesized protein in Escherichia coli; a significant portion of the proteins synthesized sedimented rapidly, presumably forming aggregates of the abnormal proteins. Protein I of the outer membrane was only slightly synthesized under these conditions.
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