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Review
. 2020 Dec 22:9:28.
doi: 10.12703/r/9-28. eCollection 2020.

An overview of the treatment of cutaneous leishmaniasis

Affiliations
Review

An overview of the treatment of cutaneous leishmaniasis

Talissa F Garza-Tovar et al. Fac Rev. .

Abstract

Leishmaniasis is a neglected tropical disease caused by species of Leishmania, with a broad spectrum of clinical manifestations, such as cutaneous, visceral, and mucocutaneous presentations. Many drugs are used for its treatment, and a current effective one is a pentavalent antimonial, especially in developing countries. In this review, we discuss recent proposed therapies as well as their side effects.

Keywords: Antimonials; Leishmaniasis; Treatment.

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Conflict of interest statement

The authors declare that they have no competing interests.No competing interests were disclosed.No competing interests were disclosed.

Figures

Figure 1.
Figure 1.. Cutaneous leishmaniasis in a Mexican patient.
Figure 2.
Figure 2.. After four doses of intralesional meglumine antimoniate.

References

    1. Torres-Guerrero E, Quintanilla-Cedillo MR, Ruiz-Esmenjaud J, et al. : Leishmaniasis: a review [version 1; peer review: 2 approved]. F1000Res. 2017; 6: 750. 10.12688/f1000research.11120.1 - DOI - PMC - PubMed
    1. Wolf Nassif P, de Mello TFP, Navasconi TR, et al. : Safety and efficacy of current alternatives in the topical treatment of cutaneous leishmaniasis: a systematic review. Parasitology. 2017; 144(8): 995–1004. 10.1017/S0031182017000385 - DOI - PubMed
    1. Aronson NE, Joya CA: Cutaneous Leishmaniasis: Updates in Diagnosis and Management. Infect Dis Clin North Am. 2019; 33(1): 101–17. 10.1016/j.idc.2018.10.004 - DOI - PubMed
    1. Uribe-Restrepo AF, Prieto MD, Cossio A, et al. : Eligibility for Local Therapies in Adolescents and Adults with Cutaneous Leishmaniasis from Southwestern Colombia: A Cross-Sectional Study. Am J Trop Med Hyg. 2019; 100(2): 306–10. 10.4269/ajtmh.18-0643 - DOI - PMC - PubMed
    1. Ramalho DB, da Silva RE, de Senna MCR, et al. : Meglumine antimoniate intralesional infiltration for localised cutaneous leishmaniasis: a single arm, open label, phase II clinical trial. Mem Inst Oswaldo Cruz. 2018; 113(9): e180200. 10.1590/0074-02760180200 - DOI - PMC - PubMed

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