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. 1988 May;79(1):24-8.
doi: 10.1007/BF00291704.

Human sperm chromosome studies in a reciprocal translocation t(2;5)

C Templado  1 , J Navarro, J Benet, A Genescà, M M Pérez, J Egozcue
Affiliations

Human sperm chromosome studies in a reciprocal translocation t(2;5)

C Templado et al. Hum Genet. 1988 May.

Abstract

Sperm chromosome complements have been studied in a man heterozygous for a reciprocal translocation t(2;5)(p11;q15). Human sperm chromosomes were obtained after fertilization of zona-free hamster eggs. A total of 75 human sperm metaphases were analysed. On the complements studied, 59 (78.6%) resulted from a 2:2 segregation and 16 (21.3%) from a 3:1 segregation, 4:0 segregation was not observed. Our results indicate that at least 36% of sperm complements were unbalanced with respect to the translocation. The frequency of other chromosome anomalies unrelated to the translocation was 16%.

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