99mTc bone scanning agents--IV. Chemical characterization of 99mTc(Sn)-pyrophosphate complexes
- PMID: 3366621
- DOI: 10.1016/0883-2897(88)90090-6
99mTc bone scanning agents--IV. Chemical characterization of 99mTc(Sn)-pyrophosphate complexes
Abstract
Various reaction mixtures for the preparation of 99Tc(Sn)-pyrophosphate were investigated by means of gel chromatography. All components were radioactively labeled. The most likely composition of the complexes, which also appear in "no carrier added" preparations, was determined. At pH 7 one complex is found with the composition TcPyp2. Two complexes are found at pH 4: TcPyp and TcPyp2. Further, at pH 7 a polymeric technetium compound is found not containing tin or pyrophosphate.