Macabre T_H2 skewing in DOCK8 deficiency

Affiliations

¹ Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Mass. Electronic address: Erin.Janssen@childrens.harvard.edu.
² Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Mass.
³ Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Mass. Electronic address: Raif.Geha@childrens.harvard.edu.

Editorial

Erin Janssen et al. J Allergy Clin Immunol. 2021 Jul.

. 2021 Jul;148(1):73-75.

doi: 10.1016/j.jaci.2021.02.025. Epub 2021 Mar 2.

¹ Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Mass. Electronic address: Erin.Janssen@childrens.harvard.edu.
² Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Mass.
³ Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Mass. Electronic address: Raif.Geha@childrens.harvard.edu.

No abstract available

Keywords: DOCK8; T(H)1; T(H)2; cell death; migration.

Comment on

Migration-induced cell shattering due to DOCK8 deficiency causes a type 2-biased helper T cell response.
Schneider C, Shen C, Gopal AA, Douglas T, Forestell B, Kauffman KD, Rogers D, Artusa P, Zhang Q, Jing H, Freeman AF, Barber DL, King IL, Saleh M, Wiseman PW, Su HC, Mandl JN. Schneider C, et al. Nat Immunol. 2020 Dec;21(12):1528-1539. doi: 10.1038/s41590-020-0795-1. Epub 2020 Oct 5. Nat Immunol. 2020. PMID: 33020661 Free PMC article.