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Review
. 2021 Feb 16;13(2):643.
doi: 10.3390/nu13020643.

Multidimensional Disadvantages of a Gluten-Free Diet in Celiac Disease: A Narrative Review

Martyna Marciniak  1 , Aleksandra Szymczak-Tomczak  1 , Dagmara Mahadea  1 , Piotr Eder  1 , Agnieszka Dobrowolska  1 , Iwona Krela-Kaźmierczak  1
Affiliations
Review

Multidimensional Disadvantages of a Gluten-Free Diet in Celiac Disease: A Narrative Review

Martyna Marciniak et al. Nutrients. .

Abstract

A gluten-free diet is the mainstay method of treatment and the prevention of celiac disease complications. However, an inadequately balanced gluten-free diet can increase the risk of obesity, negatively affect glucose and lipid metabolism, and increase the risk of the metabolic syndrome. Therefore, an adequate nutritional counselling is necessary for patients diagnosed with celiac disease in order to prevent and treat the components of the metabolic syndrome.

Keywords: cardiovascular diseases; celiac disease; diabetes mellitus t.2; dyslipidemia; gluten-free diet; gut dysbiosis; gut microbiota; metabolic syndrome; microbiome; obesity.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Gluten free diet and its risks.
See this image and copyright information in PMC

References

    1. Ludvigsson J.F., Leffler D.A., Bai J.C., Biagi F., Fasano A., Green P.H.R., Hadjivassiliou M., Kaukinen K., Kelly C.P., Leonard J.N., et al. The Oslo Definitions for Coeliac Disease and Related Terms. Gut. 2013;62:43–52. doi: 10.1136/gutjnl-2011-301346. - DOI - PMC - PubMed
    1. Husby S., Koletzko S., Korponay-Szabó I.R., Mearin M.L., Phillips A., Shamir R., Troncone R., Giersiepen K., Branski D., Catassi C., et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease. J. Pediatr. Gastroenterol. Nutr. 2012;54:136–160. doi: 10.1097/MPG.0b013e31821a23d0. - DOI - PubMed
    1. Kaswala D.H., Veeraraghavan G., Kelly C.P., Leffler D.A. Celiac Disease: Diagnostic Standards and Dilemmas. Diseases. 2015;3:86–101. doi: 10.3390/diseases3020086. - DOI - PMC - PubMed
    1. Brusca I. Overview of Biomarkers for Diagnosis and Monitoring of Celiac Disease. Adv. Clin. Chem. 2015;68:1–55. doi: 10.1016/bs.acc.2014.12.006. - DOI - PubMed
    1. Catassi C., Yachha S.K. The Global Village of Celiac Disease. Front. Celiac Dis. 2008;12:23–31. doi: 10.1159/000128610. - DOI