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Review
. 2021 Feb 11;10(4):714.
doi: 10.3390/jcm10040714.

Factors Affecting Metabolic Outcomes Post Bariatric Surgery: Role of Adipose Tissue

Sara H Keshavjee  1 , Katherine J P Schwenger  2 , Jitender Yadav  3 , Timothy D Jackson  4 , Allan Okrainec  4 , Johane P Allard  2
Affiliations
Review

Factors Affecting Metabolic Outcomes Post Bariatric Surgery: Role of Adipose Tissue

Sara H Keshavjee et al. J Clin Med. .

Abstract

Obesity is an ever-growing public health crisis, and bariatric surgery (BS) has become a valuable tool in ameliorating obesity, along with comorbid conditions such as diabetes, dyslipidemia and hypertension. BS techniques have come a long way, leading to impressive improvements in the health of the majority of patients. Unfortunately, not every patient responds optimally to BS and there is no method that is sufficient to pre-operatively predict who will receive maximum benefit from this surgical intervention. This review focuses on the adipose tissue characteristics and related parameters that may affect outcomes, as well as the potential influences of insulin resistance, BMI, age, psychologic and genetic factors. Understanding the role of these factors may help predict who will benefit the most from BS.

Keywords: adipose tissue; bariatric surgery; metabolic outcomes.

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Conflict of interest statement

S.H.K., K.J.P.S., J.Y., T.D.J. and J.P.A. have no conflict of interest to declare. Author 5 (A.O.) has relevant financial activities outside of the submitted work. He is provided an honorarium for speaking and teaching from Ethicon, Medtronic and Merk. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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