Periprosthetic joint infection with Ureaplasma parvum detected by 16S rRNA PCR
- PMID: 33674296
- PMCID: PMC7939010
- DOI: 10.1136/bcr-2020-239858
Periprosthetic joint infection with Ureaplasma parvum detected by 16S rRNA PCR
Abstract
Usual culture methods to identify pathogenic bacteria can be unsuccessful, particularly when working with fastidious organisms. We present a case of early periprosthetic knee joint infection with Ureaplasma parvum only identified using 16S ribosomal RNA PCR. This case represents the impact molecular methods of bacterial identification can have on clinical care allowing for more targeted antimicrobial therapy; something which is imperative in an era of increasing antimicrobial resistance.
Keywords: bone and joint infections; infections.
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Conflict of interest statement
Competing interests: None declared.
Similar articles
-
Early prosthetic joint infection due to Ureaplasma urealyticum: Benefit of 16S rRNA gene sequence analysis for diagnosis.J Microbiol Immunol Infect. 2019 Feb;52(1):167-169. doi: 10.1016/j.jmii.2017.07.017. Epub 2017 Oct 24. J Microbiol Immunol Infect. 2019. PMID: 29104015
-
Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland.Antimicrob Agents Chemother. 2015 Oct;59(10):6026-31. doi: 10.1128/AAC.00895-15. Epub 2015 Jul 20. Antimicrob Agents Chemother. 2015. PMID: 26195516 Free PMC article.
-
Species identification and subtyping of Ureaplasma parvum and Ureaplasma urealyticum using PCR-based assays.J Clin Microbiol. 2000 Mar;38(3):1175-9. doi: 10.1128/JCM.38.3.1175-1179.2000. J Clin Microbiol. 2000. PMID: 10699016 Free PMC article.
-
Aortic graft infection with mycoplasma (Ureaplasma urealyticum).Eur J Vasc Endovasc Surg. 1995 Oct;10(3):374-5. doi: 10.1016/s1078-5884(05)80062-0. Eur J Vasc Endovasc Surg. 1995. PMID: 7552544 Review. No abstract available.
-
Rare case of Ureaplasma parvum septic arthritis in an immunocompetent patient.BMJ Case Rep. 2020 Sep 8;13(9):e236396. doi: 10.1136/bcr-2020-236396. BMJ Case Rep. 2020. PMID: 32907868 Free PMC article. Review.
Cited by
-
Disseminated septic arthritis caused by Ureaplasma urealyticum in an immunocompromised patient with hypogammaglobulinemia after rituximab therapy.Infection. 2024 Dec;52(6):2495-2499. doi: 10.1007/s15010-024-02301-1. Epub 2024 Jun 10. Infection. 2024. PMID: 38856807 Free PMC article.
-
Ureaplasma parvum Septic Arthritis, a Clinic Challenge.Diagnostics (Basel). 2022 Oct 6;12(10):2416. doi: 10.3390/diagnostics12102416. Diagnostics (Basel). 2022. PMID: 36292105 Free PMC article.
References
-
- Ostapchuk M, Roberts DM, Haddy R. Community-Acquired pneumonia in infants and children. Am Fam Physician 2004;70:899–908. - PubMed
-
- Mandell G, Bennett J, Dolin R. Principles and practice of infectious diseases. 9th edn. Elsevier, 2020.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources