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Observational Study
. 2021 Mar 5;11(1):5284.
doi: 10.1038/s41598-021-84808-3.

Macular irregularities of optical coherence tomographic vertical cross sectional images in school age children

Takehiro Yamashita  1 , Hiroto Terasaki  1 , Ryo Asaoka  2   3 , Naoya Yoshihara  1 , Naoko Kakiuchi  1 , Taiji Sakamoto  4
Affiliations
Observational Study

Macular irregularities of optical coherence tomographic vertical cross sectional images in school age children

Takehiro Yamashita et al. Sci Rep. .

Abstract

The purpose of this study was to compare the incidences of macular irregularities of elementary school (ES) and junior high school (JHS) students. This was a prospective cross-sectional observational study of 122 right eyes of 122 ES students (8-9 years) and 173 right eyes of 173 JHS students (12-13 years). Vertical cross-sectional images of the macula were obtained by optical coherence tomography. The eyes were classified based on the vertical symmetry of the posterior pole, and then sub-classified as convex-, flat-, concave-, or dome-shaped based on the direction of the curvature of the retinal pigment epithelium. One hundred and two eyes (83.6%) were placed in the symmetrical group in the ES students and 149 eyes (86.1%) in the JHS students. Twenty eyes (16.4%) were placed in the asymmetric groups in the ES students and 24 eyes (13.9%) in the JHS students. In symmetrical group, 78 and 118 eyes had a convex-shape (76.4 and 79.2%), followed by 22 and 29 eyes of dome-shaped group (21.6 and 19.4%) in ES and JHS students respectively. Because the incidences of the posterior pole shapes were not significantly different between the groups, it is likely that the macular irregularities develop before the age of ES.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Magnification of the optical coherence tomographic (OCT) vertical cross-sectional image. First, the original 2X B-scan image (A) was vertically expanded 4X (B, vertical-to-horizontal ratio, 8:1) for easier detection of the macular shape. Second, the image was rotated to make the ellipsoid zone around the fovea symmetrical (C).
Figure 2
Figure 2
Classification of shapes of macular vertical cross-sectional images. The OCT images were classified based upon its vertical symmetry. Images in (A, B), and (C) are symmetrical, and images in (D) and (E) are asymmetrical. The images are then sub-classified into convex-shaped (A, D upper part), flat-shaped (B), dome-shaped (C, D lower part, E upper part), and concave-shaped (E lower part) according to the retinal pigment epithelium curvature. Red lines are horizontal straight lines.
See this image and copyright information in PMC

References

    1. Gaucher D, et al. Dome-shaped macula in eyes with myopic posterior staphyloma. Am. J. Ophthalmol. 2008;145:909–914. doi: 10.1016/j.ajo.2008.01.012. - DOI - PubMed
    1. Caillaux V, et al. Morphologic characterization of dome-shaped macula in myopic eyes with serous macular detachment. Am. J. Ophthalmol. 2013;156:958–967. doi: 10.1016/j.ajo.2013.06.032. - DOI - PubMed
    1. Imamura Y, Iida T, Maruko I, Zweifel SA, Spaide RF. Enhanced depth imaging optical coherence tomography of the sclera in dome-shaped macula. Am. J. Ophthalmol. 2011;151:297–302. doi: 10.1016/j.ajo.2010.08.014. - DOI - PubMed
    1. Ohno-Matsui K, Jonas JB, Spaide RF. Macular Bruch's membrane holes in choroidal neovascularization-related myopic macular atrophy by swept-source optical coherence tomography. Am. J. Ophthalmol. 2015;162:133–139. doi: 10.1016/j.ajo.2015.11.014. - DOI - PubMed
    1. Ohno-Matsui K, Jonas JB, Spaide RF. Macular Bruch membrane holes in highly myopic patchy chorioretinal atrophy. Am. J. Ophthalmol. 2016;166:22–28. doi: 10.1016/j.ajo.2016.03.019. - DOI - PubMed

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