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Review
. 2021 Jun;41(6):1216-1224.
doi: 10.1038/s41372-021-01015-8. Epub 2021 Mar 5.

80 Years of vision: preventing blindness from retinopathy of prematurity

Edward H Wood  1   2 , Emmanuel Y Chang  3 , Kinley Beck  4 , Brandon R Hadfield  5 , Amy R Quinn  5 , Clio Armitage Harper 3rd  6   7   8
Affiliations
Review

80 Years of vision: preventing blindness from retinopathy of prematurity

Edward H Wood et al. J Perinatol. 2021 Jun.

Abstract

Retinopathy of prematurity (ROP) is one of the leading yet preventable causes of childhood blindness worldwide. The purpose of this review is to provide a practical template for observational and treatment methods in order to reduce the overall incidence of any ROP and to improve both short-term and long-term outcomes once Type 1 ROP (treatable ROP) develops.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Delayed retinal vascular maturation following anti-VEGF therapy requires surveillance.
Left eye of a child with type 1 ROP who had undergone two anti-VEGF injections at an outside hospital as an infant and did not receive follow-up with fluorescein angiography and laser until 18 months of age, disclosing continued neovascular activity with severe macular distortion. The fellow (right) eye of the child had also received three anti-VEGF injections at an outside hospital and was phthisical.
See this image and copyright information in PMC

References

    1. Blencowe H, Lawn JE, Vazquez T, Fielder A, Gilbert C. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010. Pediatr Res. 2013;74:35–49. - PMC - PubMed
    1. Retinopathy of Prematurity. https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseas... (accessed 18 Nov 2020).
    1. Lambert SR, Lyons CJ. Taylor and hoyt’s pediatric ophthalmology and strabismus. 5th ed. England: Elsevier Health Sciences: London; 2016.
    1. Locke JC. Retrolental fibroplasia definitive role of oxygen administration in its etiology. AMA Arch Ophthalmol. 1954;51:73–79. - PubMed
    1. Szewczyk TS. Retrolental fibroplasia and related ocular diseases; classification, etiology, and prophylaxis. Am J Ophthalmol. 1953;36:1336–61. - PubMed

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