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Comment
. 2021 May;62(5):674-676.
doi: 10.1111/jcpp.13408. Epub 2021 Mar 6.

Commentary: Schizophrenia prevention and prodromal psychosis in children and adolescents

Jerome H Taylor  1   2 , Zeeshan M Huque  2
Affiliations
Comment

Commentary: Schizophrenia prevention and prodromal psychosis in children and adolescents

Jerome H Taylor et al. J Child Psychol Psychiatry. 2021 May.

Abstract

Catalan and colleagues aggregated findings related to detection, prognosis, and intervention in Clinical High Risk for Psychosis (CHR-P) children and adolescents through October 7, 2019 (Catalan et al., 2020). While a sufficient number of studies were available to meta-analytically summarize evidence on detection and prognosis, the authors highlight the need for more studies on interventions, including cognitive behavioral therapy for psychosis, in CHR-P youth. Further research on the biological and neural correlates of CHR-P in children and adolescents is also needed. Though results from the few existing biomarker studies in CHR-P youth were included in the systematic review, disparate study methodologies and outcomes prohibited biomarker study meta-analysis.

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References

    1. Catalan, A., Salazar de Pablo, G., Serrano, J.V., Mosillo, P., Baldwin, H., Fernandez-Rivas, A., … & Fusar-Poli, P. (2020). Annual Research Review: Prevention of psychosis in adolescents - systematic review and meta-analysis of advances in detection, prognosis and intervention. Journal of Child Psychology and Psychiatry. (in press). https://doi.org/10.1111/jcpp.13322
    1. Fusar-Poli, P., Cappucciati, M., Borgwardt, S., Woods, S.W., Addington, J., Nelson, B., … & McGuire, P.K. (2016). Heterogeneity of psychosis risk within individuals at clinical high risk: a meta-analytical stratification. JAMA Psychiatry, 73, 113-120.
    1. Fusar-Poli, P., Nelson, B., Valmaggia, L., Yung, A.R., & McGuire, P.K. (2014). Comorbid depressive and anxiety disorders in 509 individuals with an at-risk mental state: impact on psychopathology and transition to psychosis. Schizophrenia Bulletin, 40, 120-131.
    1. Londono Tobon, A., Flores, J.M., Taylor, J.H., Johnson, I., Landeros-Weisenberger, A., Aboiralor, O., … & Bloch, M.H. (2021). Racial implicit associations in psychiatric diagnosis, treatment, and compliance expectations. Academic Psychiatry. https://doi.org/10.1007/s40596-020-01370-2
    1. Perkins, D.O., Jeffries, C.D., Addington, J., Bearden, C.E., Cadenhead, K.S., Cannon, T.D., … & Heinssen, R. (2014). Towards a psychosis risk blood diagnostic for persons experiencing high-risk symptoms: preliminary results from the NAPLS project. Schizophrenia Bulletin, 41, 419-428.

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