Conflicts of interest Dr Bissonnette is a consultant with honoraria for Bausch Health Companies Inc and Boston Pharmaceuticals; an investigator with grants/research funding for AbbVie Inc and Escalier Biosciences, Inc; an advisor with honoraria and an investigator with grants/research funding for BMS, Boehringer Ingelheim, Eli Lilly and Company, and Pfizer Inc; a consultant with honoraria and an investigator with grants/research funding for Janssen-Ortho Inc, Sienna Biopharmaceuticals, Inc, and Valeant Pharmaceuticals North America LLC; and an advisor, a consultant with honoraria, and an investigator with grants/research funding for Dermavant Sciences, Inc. Dr Gold is an investigator, consultant, and speaker with honorarium for Leo Pharma; an investigator with honorarium for Incyte; a consultant and speaker with honorarium for Mayne Pharma and Taro Pharmaceutical Industries; an investigator and consultant for Ortho Dermatologics and Sun; and a consultant with honorarium and an investigator for Dermavant Sciences, Inc. Dr Rubenstein is an employee of Dermavant Sciences, Inc with stock options. Dr Tallman is an employee of Dermavant Sciences, Inc with stock options. Dr Armstrong has served as a research investigator or scientific advisor to AbbVie, BI, BMS, EPI, Incyte, Leo, UCB, Janssen, Lilly, Novartis, Ortho Dermatologics, Sun, Dermavant Sciences, Inc, Dermira, Sanofi, Regeneron, Pfizer, and Modmed.