Conflicts of interest Dr Bissonnette is a consultant with honoraria for Bausch Health Companies, Inc and Boston Pharmaceuticals; an investigator with grants/research funding for AbbVie, Inc and Escalier Biosciences, Inc; an advisor with honoraria and an investigator with grants/research funding for BMS, Boehringer Ingelheim, Eli Lilly and Company, and Pfizer, Inc; a consultant with honoraria and an investigator with grants/research funding for Janssen-Ortho, Inc, Sienna Biopharmaceuticals, Inc, and Valeant Pharmaceuticals North America LLC; and an advisor, a consultant with honoraria, and an investigator with grants/research funding for Dermavant Sciences, Inc. Dr Gold is an investigator, consultant, and speaker with honorarium for Leo Pharma; an investigator with honorarium for Incyte; a consultant and speaker with honorarium from Mayne Pharma and Taro Pharmaceutical Industries; an investigator and consultant for Ortho Dermatologics and Sun; and a consultant with honorarium and an investigator for Dermavant Sciences, Inc. Drs Rubenstein and Tallman are both employees of Dermavant Sciences, Inc with stock options. Dr Armstrong has served as a research investigator and/or scientific advisor for AbbVie, BI, BMS, EPI, Incyte, Leo, UCB, Janssen, Lilly, Novartis, Ortho Dermatologics, Sun, Dermavant Sciences, Inc, Dermira, Sanofi, Regeneron, Pfizer, and Modmed.