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. 2021 Mar 6;7(1):21.
doi: 10.1186/s40981-021-00424-0.

Remimazolam anesthesia for cardiac surgery with cardiopulmonary bypass: a case report

Kota Saito  1 , Sho Ohno  2 , Makishi Maeda  2 , Naoyuki Hirata  2 , Michiaki Yamakage  2
Affiliations

Remimazolam anesthesia for cardiac surgery with cardiopulmonary bypass: a case report

Kota Saito et al. JA Clin Rep. .

Abstract

Background: Remimazolam has less cardiovascular depressant effects than propofol in non-cardiac surgical patients. However, the efficacy and safety of remimazolam in cardiac surgery with cardiopulmonary bypass (CPB) have not been reported. We present a case of successful anesthetic management using remimazolam in cardiac surgery with CPB.

Case presentation: A 76-year-old female was scheduled for mitral valve repair, tricuspid annuloplasty, maze procedure, and left atrial appendage closure. We used remimazolam in induction (6.0 mg/kg/h) and maintenance (0.6-1.0 mg/kg/h) of general anesthesia, and the bispectral index value was maintained in the range of 36 to 48 including the period of CPB. Hemodynamics, mixed venous oxygen saturation, and bilateral regional cerebral oxygen saturation were maintained within acceptable ranges. There was no intraoperative awareness/recall or serious complications associated with remimazolam throughout the perioperative period.

Conclusions: Remimazolam can be used the same as other existing anesthetics in cardiac surgery with CPB.

Keywords: Cardiac surgery; Cardiopulmonary bypass; Remimazolam.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Anesthetic record. sBP, systolic blood pressure; dBP, diastolic blood pressure; BIS, bispectal index
See this image and copyright information in PMC

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