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Review
. 2021 Feb;36(1):36-40.
doi: 10.3803/EnM.2021.104. Epub 2021 Feb 24.

Best Achievements in Translational and Basic Thyroidology in 2020

Sun Wook Cho  1 , Young Joo Park  1   2
Affiliations
Review

Best Achievements in Translational and Basic Thyroidology in 2020

Sun Wook Cho et al. Endocrinol Metab (Seoul). 2021 Feb.

Abstract

This review discusses articles published in 2020 that presented noteworthy achievements in translational and basic thyroidology. Previously unresolved questions about thyroid hormone receptor actions and signaling mechanisms were answered using various novel in vitro and in vivo models. Using high resolution cryo-electron microscopy, the fine functional structure of thyroglobulin was demonstrated, and new insights into the pathogenesis of thyroid disease were achieved, with a focus on research into thyroid-disrupting chemicals and the gut microbiome. Novel therapeutic approaches were tried in the field of advanced thyroid cancer treatments.

Keywords: Endocrine disruptors; Gastrointestinal microbiome; Receptors, thyroid hormone; Thyroglobulin; Thyroid neoplasm.

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Conflict of interest statement

CONFLICTS OF INTEREST

No potential conflict of interest relevant to this article was reported.

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