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. 2021 Mar 25;51(2):86-94.
doi: 10.4041/kjod.2021.51.2.86.

Effect of micro-osteoperforations on external apical root resorption: A randomized controlled trial

Azaitun Akma Shahrin  1 , Sarah Haniza Abdul Ghani  1 , Noraina Hafizan Norman  1
Affiliations

Effect of micro-osteoperforations on external apical root resorption: A randomized controlled trial

Azaitun Akma Shahrin et al. Korean J Orthod. .

Abstract

Objective: This study aimed to investigate the effect of micro-osteoperforations (MOPs) on external apical root resorption (EARR) during the initial orthodontic alignment phase of maxillary anterior crowding.

Methods: Thirty patients (25 females, 5 males; mean age, 22.66 ± 3.27 years) who presented with moderate crowding of the upper labial segment and underwent extraction-based fixed appliance treatment were recruited. They were randomly allocated to receive adjunctive therapy with MOPs (n = 15) or treatment with fixed appliances only (control group; n = 15). EARR was measured from long-cone periapical radiographs taken at the start and the sixth month of treatment. A correction factor for the enlargement difference was used to calculate EARR. Data were analyzed with descriptive statistics and repeated-measures analysis of variance.

Results: The mean root lengths of 168 teeth were measured and showed no statistically significant difference (p > 0.05) after six months of fixed appliance treatment in the MOP (mean difference [MD] = 0.13 mm; 95% confidence interval [CI] = -0.10-0.35) and control group (MD = 0.14 mm; 95% CI = -0.10-0.37). Most of the roots in the MOP and control groups (42.86% and 52.38%, respectively) showed only mild resorption. Less than 8% of the roots in both groups (7.14% in the MOP group and 4.76% in the control group) showed moderate resorption.

Conclusions: Acceleration of orthodontic tooth movement with adjunctive MOPs therapy during the alignment phase does not exacerbate EARR in patients with moderate crowding of the upper labial segment in comparison with controls.

Keywords: External apical root resorption; Iatrogenic effect; Micro-osteoperforations; Orthodontic alignment.

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Conflict of interest statement

CONFLICTS OF INTEREST

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
Intraoral periapical (IOPA) radiographs. A, Pre-IOPA taken before orthodontic treatment. B, Post-IOPA repeated after 6 months of treatment.
Figure 2
Figure 2
Measurements of total root and crown length at (A) T1: pre-treatment, (B) T2: post-treatment after 6 months were performed on intraoral periapical radiographs at the median point of the tooth axis. R1, pre-treatment root length; R2, post-treatment root length; C1, pre-treatment crown length; C2, post-treatment crown length.
Figure 3
Figure 3
Consolidated Standards of Reporting Trials (CONSORT) study flow diagram. MOP, micro-osteoperforation.
See this image and copyright information in PMC

References

    1. Iglesias-Linares A, Hartsfield JK., Jr Cellular and molecular pathways leading to external root resorption. J Dent Res. 2017;96:145–52. doi: 10.1177/0022034516677539. - DOI - PMC - PubMed
    1. Fahey T, Stephenson P. Root resorption during fixed appliance therapy- mechanism, risk factors and prognosis. Orthod Update. 2016;9:96–9. doi: 10.12968/ortu.2016.9.3.96. - DOI
    1. Nowrin SA, Jaafar S, Ab Rahman N, Basri R, Alam MK, Shahid F. Association between genetic polymorphisms and external apical root resorption: a systematic review and meta-analysis. Korean J Orthod. 2018;48:395–404. doi: 10.4041/kjod.2018.48.6.395. - DOI - PMC - PubMed
    1. Roscoe MG, Meira JB, Cattaneo PM. Association of orthodontic force system and root resorption: a systematic review. Am J Orthod Dentofacial Orthop. 2015;147:610–26. doi: 10.1016/j.ajodo.2014.12.026. - DOI - PubMed
    1. Weiland F. Constant versus dissipating forces in orthodontics: the effect on initial tooth movement and root resorption. Eur J Orthod. 2003;25:335–42. doi: 10.1093/ejo/25.4.335. - DOI - PubMed

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