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. 2021 Sep 10;37(9):1305-1307.
doi: 10.2116/analsci.21N001. Epub 2021 Mar 5.

Gold-Silver and Gold-Palladium Alloy Nanoparticles as Mass-Probes for Immunosensing

Maiko Akasaka  1 , Tomoki Nishi  1 , Yasuro Niidome  2
Affiliations
Free article

Gold-Silver and Gold-Palladium Alloy Nanoparticles as Mass-Probes for Immunosensing

Maiko Akasaka et al. Anal Sci. .
Free article

Abstract

Silver or palladium shelled gold nanoparticles were fused into alloy nanoparticles by pulsed-laser irradiation. The alloy nanoparticles could carry antibodies on their surfaces without affecting their immune functionalities and interact selectively with antigens on a blotting membrane. Silver or palladium ions desorbed from the alloy nanoparticles as reporter ions upon the UV laser irradiation in a mass spectrometer.

Keywords: Alloy nanoparticle; core-shell nanoparticle; immune functional nanoparticle; mass probe.

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