Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jun 21;2(1):e000015.
doi: 10.1136/bmjno-2019-000015. eCollection 2020.

Real-life outcomes in spasticity management: features affecting goal achievement

Affiliations

Real-life outcomes in spasticity management: features affecting goal achievement

Rajiv Singh et al. BMJ Neurol Open. .

Abstract

Background/objective: Spasticity is a complex and common condition but there is a lack of 'real-world' data on goal setting and spasticity treatment, as well as identifying those features that might be associated with goal achievement. Our aim was to provide such data.

Methods: Prospective attenders at a multi-disciplinary spasticity clinic over 2 years followed for consecutive appointments. Patient demographics and doses of botulinum toxin injected were documented. Main outcome was achievement of a primary goal but secondary goals were also recorded. Independent variables were examined for association to the outcome.

Results: A total of 606 goals were set in 224 patients. The majority (75.2%) were achieved with similar levels across active (72.5%), passive (75.7%) and pain (78.6%) goals. However, in terms of the primary goal, active primary goals were achieved less frequently (59.7%) than non-active primary goal (74.2%). A logistic regression confirmed that this was the only independent variable associated with primary goal achievement. The majority of patients (61.6%) required changes to their treatment between appointments, irrespective of time since diagnosis, age or aetiology.

Conclusions: Most goals set in spasticity clinic can be achieved irrespective of type of goal. However, active goals may be harder to accomplish when they are set as a primary goal. This may reflect the desire of individuals to prioritise a desirable goal rather than one that is achievable. While goal setting is important in the management of spasticity patients, very few patient or treatment factors are associated with outcome prediction. Further work needs to identify features that may predict successful outcome.

Keywords: botulinum toxin; rehabilitation; spasticity; stroke; traumatic brain injury.

PubMed Disclaimer

Conflict of interest statement

Competing interests: Both authors have an interest in goal setting and outcome measurement.

Figures

Figure 1
Figure 1
Muscles injected in 206 individuals. Adduc, adductor compartment thigh; BB, biceps/brachialis; BR, brachioradialis; FCR, flexor carpi radialis; FCU, flexor carpi ulnaris; FDL, flexor digitorum longus; FDP, flexor digitorum profundus; FDS, flexor digitorum superficialis; FHB, flexor hallucis brevis; FHL, flexor hallucis longus; FPL, flexor pollicis longus; HS, hamstrings; PT, pronator teres; TP, tibialis posterior.

Similar articles

Cited by

References

    1. Spasticity in Adults Management using botulinum toxin. Royal College of Physicians, 2009.
    1. Elia AE, Filippini G, Calandrella D, et al. . Botulinum neurotoxins for post-stroke spasticity in adults: a systematic review. Mov Disord 2009;24:801–12. 10.1002/mds.22452 - DOI - PubMed
    1. Turner-Stokes L, Fheodoroff K, Jacinto J, et al. . Results from the Upper Limb International Spasticity Study-II (ULISII):a large, international, prospective cohort study investigating practice and goal attainment following treatment with botulinum toxin A in real-life clinical management. BMJ Open 2013;3:e002771. 10.1136/bmjopen-2013-002771 - DOI - PMC - PubMed
    1. Verplancke D, Snape S, Salisbury CF, et al. . A randomized controlled trial of botulinum toxin on lower limb spasticity following acute acquired severe brain injury. Clin Rehabil 2005;19:117–25. 10.1191/0269215505cr827oa - DOI - PubMed
    1. Yablon SA, Agana BT, Ivanhoe CB, et al. . Botulinum toxin in severe upper extremity spasticity among patients with traumatic brain injury: an open-labeled trial. Neurology 1996;47:939–44. 10.1212/WNL.47.4.939 - DOI - PubMed

LinkOut - more resources