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Review
. 2021 May;68(5):e28919.
doi: 10.1002/pbc.28919. Epub 2021 Mar 7.

Proton therapy: A therapeutic opportunity for aggressive pediatric meningioma

Barbara Rombi  1   2 , Alessandro Ruggi  3 , Iacopo Sardi  4 , Mino Zucchelli  5 , Mirko Scagnet  6 , Francesco Toni  7 , Silvia Cammelli  2 , Giulia Giulietti  3 , Viscardo Paolo Fabbri  8 , Francesca Gianno  9 , Maurizio Amichetti  1 , Torunn Ingrid Yock  10 , Alessio Giuseppe Morganti  2 , Andrea Pession  3 , Fraia Melchionda  3
Affiliations
Review

Proton therapy: A therapeutic opportunity for aggressive pediatric meningioma

Barbara Rombi et al. Pediatr Blood Cancer. 2021 May.

Abstract

Meningiomas are an extremely rare histology among pediatric brain tumors, and there is a shortage of literature on their management. Proton therapy is currently used safely and effectively for many types of both pediatric and adult cancer, and its main advantage is the sparing of healthy tissues from radiation, which could translate in the reduction of late side effects. We review the literature on radiotherapy and proton therapy for pediatric meningiomas and report clinical outcomes for two aggressive pediatric meningiomas we treated with protons. Proton therapy might be a safe and effective therapeutic option for this rare subgroup of tumors.

Keywords: pediatric brain tumors; pediatric meningioma; proton therapy; radiotherapy.

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References

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