The Home-Based Sleep Laboratory
- PMID: 33682729
- PMCID: PMC8385505
- DOI: 10.3233/JPD-202412
The Home-Based Sleep Laboratory
Abstract
Sleep disturbances are prevalent in neurodegenerative diseases in general, and in Parkinson's disease (PD) in particular. Recent evidence points to the clinical value of sleep in disease progression and improving quality of life. Therefore, monitoring sleep quality in an ongoing manner at the convenience of one's home has the potential to improve clinical research and to contribute to significantly better personalized treatment. Further, precise mapping of sleep patterns of each patient can contribute to a better understanding of the disease, its progression and the appropriate medical treatment. Here we review selective, state-of-the-art, home-based devices for assessing sleep and sleep related disorders. We highlight the large potential as well as the main challenges. In particular, we discuss medical validity, standardization and regulatory concerns that currently impede widespread clinical adoption of existing devices. Finally, we propose a roadmap with the technological and scientific steps that are required to impact PD research and treatment.
Keywords: Movement disorders; flexible electronics; skin electronics; sleep disorders; smart skin; wearable electrophysiology.
Conflict of interest statement
YH declares financial interest in X-trodes Ltd., which holds the licensing rights of the skin technology cited in this paper. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in, or financial conflict with the subject matter or materials discussed in the manuscript, apart from those disclosed.
Figures
Similar articles
-
Shedding Light on Nocturnal Movements in Parkinson's Disease: Evidence from Wearable Technologies.Sensors (Basel). 2020 Sep 10;20(18):5171. doi: 10.3390/s20185171. Sensors (Basel). 2020. PMID: 32927816 Free PMC article. Review.
-
Disturbances of Sleep and Alertness in Parkinson's Disease.Curr Neurol Neurosci Rep. 2018 Apr 19;18(6):29. doi: 10.1007/s11910-018-0838-2. Curr Neurol Neurosci Rep. 2018. PMID: 29675716 Review.
-
The Spectrum of Sleep Disorders in Parkinson Disease: A Review.Chest. 2021 Feb;159(2):818-827. doi: 10.1016/j.chest.2020.09.099. Epub 2020 Sep 19. Chest. 2021. PMID: 32956712 Review.
-
Recognition and diagnosis of sleep disorders in Parkinson's disease.J Neurol. 2012 Oct;259(10):2031-40. doi: 10.1007/s00415-012-6505-7. Epub 2012 Apr 26. J Neurol. 2012. PMID: 22535255 Free PMC article. Review.
-
Sleep Dysfunction in Parkinson's Disease.Int Rev Neurobiol. 2017;133:719-742. doi: 10.1016/bs.irn.2017.05.033. Epub 2017 Jul 10. Int Rev Neurobiol. 2017. PMID: 28802939 Review.
Cited by
-
A scoping review of neurodegenerative manifestations in explainable digital phenotyping.NPJ Parkinsons Dis. 2023 Mar 30;9(1):49. doi: 10.1038/s41531-023-00494-0. NPJ Parkinsons Dis. 2023. PMID: 36997573 Free PMC article.
-
Excessive rest time during active phase is reliably detected in a mouse model of myotonic dystrophy type 1 using home cage monitoring.Front Behav Neurosci. 2023 Mar 2;17:1130055. doi: 10.3389/fnbeh.2023.1130055. eCollection 2023. Front Behav Neurosci. 2023. PMID: 36935893 Free PMC article.
References
-
- Postuma RB (2014) Prodromal Parkinson’s disease - Using REM sleep behavior disorder as a window. Parkinsonism Relat Disord 20(Suppl 1), S1–4. - PubMed
-
- Paparrigopoulos TJ (2005) REM sleep behaviour disorder: Clinical profiles and pathophysiology. Int Rev Psychiatry 17, 293–300. - PubMed
-
- Cesari M, Christensen JAE, Muntean ML, Mollenhauer B, Sixel-Döring F, Sorensen HBD, Trenkwalder C, Jennum P (2020) A data-driven system to identify REM sleep behavior disorder and to predict its progression from the prodromal stage in Parkinson’s disease. Sleep Med, doi: 10.1016/j.sleep.2020.04.010 - DOI - PubMed
-
- Meloni M, Bortolato M, Cannas A, Laccu I, Figorilli M, Congiu P, Defazio G, Meloni F, Puligheddu M (2020) Association between dopaminergic medications and REM sleep behavior disorder in Parkinson’s disease: A preliminary cohort study. J Neurol 267, 2926–2931. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical