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. 2021 Jan 28;92(1):e2021073.
doi: 10.23750/abm.v92i1.11273.

Aging delay: of mice and men

Vladimir Anisimov  1
Affiliations

Aging delay: of mice and men

Vladimir Anisimov. Acta Biomed. .

Abstract

The evaluation of the safety of a drug in rodents that may be used as geroprotectors is a challenge of current times. In the paper, we discuss approaches to long-term assays for selection of potent aging delay drugs for humans. Priority is given to methods combining evaluation of carcinogenic safety and life-spanning potential. The use of such methods will be time-efficient and economically feasible.

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Conflict of interest statement

Each author declares that he or she has no commercial associations (e.g. consultancies, stock ownership, equity interest, patent/licensing arrangement etc.) that might pose a conflict of interest in connection with the submitted article.

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