Medical algorithm: Diagnosis and treatment of hypersensitivity reactions to cancer chemotherapy

Ricardo Madrigal-Burgaleta^{1

2}, Paula Vazquez-Revuelta^{2

3}, Jaume Marti-Garrido^{2

3}, Ramon Lleonart-Bellfill^{2

3}, Fawzia Runa Ali¹, Emilio Alvarez-Cuesta⁴

Affiliations

¹ Allergy & Severe Asthma Service, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
² Drug Desensitisation Centre, Catalan Institute of Oncology, Barcelona, Spain.
³ Allergy Service, Internal Medicine Department, Bellvitge University Hospital, Barcelona, Spain.
⁴ Allergy Division, Former Head, Ramon y Cajal University Hospital, Madrid, Spain.

Ricardo Madrigal-Burgaleta et al. Allergy. 2021 Aug.

. 2021 Aug;76(8):2636-2640.

doi: 10.1111/all.14810. Epub 2021 May 20.

Ricardo Madrigal-Burgaleta^{1

2}, Paula Vazquez-Revuelta^{2

3}, Jaume Marti-Garrido^{2

3}, Ramon Lleonart-Bellfill^{2

3}, Fawzia Runa Ali¹, Emilio Alvarez-Cuesta⁴

¹ Allergy & Severe Asthma Service, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
² Drug Desensitisation Centre, Catalan Institute of Oncology, Barcelona, Spain.
³ Allergy Service, Internal Medicine Department, Bellvitge University Hospital, Barcelona, Spain.
⁴ Allergy Division, Former Head, Ramon y Cajal University Hospital, Madrid, Spain.

No abstract available

Keywords: Drug allergy; anaphylaxis; de-labelling; drug desensitisation; personalised medicine.

References

1. Madrigal-Burgaleta R, Bernal-Rubio L, Berges-Gimeno MP, Carpio-Escalona LV, Gehlhaar P, Alvarez-Cuesta E. A large single-hospital experience using drug provocation testing and rapid drug desensitization in hypersensitivity to antineoplastic and biological agents. J Allergy Clin Immunol Pract. 2019;7(2):618-632.
1. Alvarez-Cuesta E, Madrigal-Burgaleta R, Angel-Pereira D, et al. Delving into cornerstones of hypersensitivity to antineoplastic and biological agents: Value of diagnostic tools prior to desensitization. Allergy 2015;70(7):784-794.
1. Hong DI, Madrigal-Burgaleta R, Banerji A, Castells M, Alvarez-Cuesta E. Controversies in Allergy: Chemotherapy reactions, desensitize or de-label? J Allergy Clin Immunol Pract. 2020;8(9):2907-2915.e1.
1. Madrigal-Burgaleta R, Vazquez-Revuelta P, Marti-Garrido J, Lleonart R, Ali FR, Alvarez-Cuesta E. Importance of diagnostics prior to desensitization in new drug hypersensitivity: chemotherapeutics and biologicals. Curr Treat Options Allergy. 2020;7(1):1-13.
1. Sloane D, Govindarajulu U, Harrow-Mortelliti J, et al. Safety, costs, and efficacy of rapid drug desensitizations to chemotherapy and monoclonal antibodies. J Allergy Clin Immunol Pract. 2016;4(3):497-504.