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Comment
. 2021 Mar 9;54(3):401-403.
doi: 10.1016/j.immuni.2021.02.011.

A totally OSM gift to astrocytes relieves inflammation

Angela A Wang  1 , Jennifer L Gommerman  2
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Free article
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A totally OSM gift to astrocytes relieves inflammation

Angela A Wang et al. Immunity. .
Free article

Abstract

Dectin-1 is known for promoting anti-fungal responses through the signaling molecule Card9. In this issue of Immunity, Deerhake et al. now report that during autoimmune neuroinflammation, Dectin-1 can promote a neuroprotective feed-forward pathway through Card9-independent upregulation of Oncostatin M.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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