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. 2021 Mar 4:15:983-990.
doi: 10.2147/OPTH.S285628. eCollection 2021.

The PanOptix Trifocal IOL vs the ReSTOR 2.5 Active Focus and ReSTOR 3.0-Add Multifocal Lenses: A Study of Patient Satisfaction, Visual Disturbances, and Uncorrected Visual Performance

John A Hovanesian  1 , Michael Jones  2 , Quentin Allen  3
Affiliations

The PanOptix Trifocal IOL vs the ReSTOR 2.5 Active Focus and ReSTOR 3.0-Add Multifocal Lenses: A Study of Patient Satisfaction, Visual Disturbances, and Uncorrected Visual Performance

John A Hovanesian et al. Clin Ophthalmol. .

Abstract

Purpose: To compare spectacle independence, patient-reported outcomes (PROs), and dysphotopsia after multifocal intraocular lens (IOL) implantation with the AcrySof PanOptix trifocal or the ReSTOR +2.5/3.0 D or ReSTOR +2.5 D mini-monovision multifocal IOL.

Patients and methods: Prospective, open-label, multicenter analysis of PROs, spectacle independence, and satisfaction among patients undergoing cataract surgery who had been implanted at least 1 month previously with AcrySof IQ PanOptix or PanOptix Toric trifocal (n = 59) IOLs bilaterally. Results were compared to outcomes from a similar study with the AcrySof ReSTOR 2.5/3.0 or the ReSTOR ActiveFocus 2.5 mini-monovision lens [n = 191]).

Results: Spectacle independence was significantly higher in the PanOptix cohort, with 83% of patients "never" needing glasses for any activity versus 36% in the ReSTOR 2.5 mini-monovision and 34% in the ReSTOR 2.5/3.0 cohorts. No significant differences in patient satisfaction rates were reported between the three cohorts. Glare and halo were rated "extremely" noticeable more with the PanOptix (10%) than with the ReSTOR 2.5 mini-monovision (1%) or ReSTOR 2.5/3.0 (3%). BCVA differences were not statistically significant, and no new safety concerns were reported.

Conclusion: The AcrySof PanOptix trifocal provides significantly greater spectacle independence across all measured activities than the AcrySof ReSTOR multifocal IOLs.

Keywords: cataract surgery; glare; multifocal intraocular lens; spectacle independence.

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Conflict of interest statement

Dr John A Hovanesian reports grants, personal fees from Alcon, during the conduct of the study; personal fees from Alcon, outside the submitted work. Dr Quentin Allen is a consultant for Alcon. The authors report no other conflicts of interest in this work.

Figures

Figure 1
Figure 1
Patient demographic data.
Figure 2
Figure 2
Overall patient satisfaction.
Figure 3
Figure 3
Overall spectacle independence.
Figure 4
Figure 4
Need for spectacle use.
Figure 5
Figure 5
Incidence of glare and haloes.
See this image and copyright information in PMC

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