A Green Light for Stop Mutations

Malena Cohen-Cymberknoh^{1

2

3}, Mordechai Slae^{1

4

5}, Michael Wilschanski^{1

4

5}

Affiliations

¹ Faculty of Medicine Hebrew University Jerusalem, Israel.
² Pediatric Pulmonology Unit.
³ Cystic Fibrosis Center Hadassah-Hebrew University Medical Center Jerusalem, Israel.
⁴ Cystic Fibrosis Center and.
⁵ Pediatric Gastroenterology Unit Hadassah-Hebrew University Medical Center Jerusalem, Israel.

Editorial

Malena Cohen-Cymberknoh et al. Am J Respir Cell Mol Biol. 2021 May.

. 2021 May;64(5):531-532.

doi: 10.1165/rcmb.2021-0060ED.

Malena Cohen-Cymberknoh^{1

2

3}, Mordechai Slae^{1

4

5}, Michael Wilschanski^{1

4

5}

¹ Faculty of Medicine Hebrew University Jerusalem, Israel.
² Pediatric Pulmonology Unit.
³ Cystic Fibrosis Center Hadassah-Hebrew University Medical Center Jerusalem, Israel.
⁴ Cystic Fibrosis Center and.
⁵ Pediatric Gastroenterology Unit Hadassah-Hebrew University Medical Center Jerusalem, Israel.

No abstract available

Comment on

Novel Correctors and Potentiators Enhance Translational Readthrough in CFTR Nonsense Mutations.
Mutyam V, Sharma J, Li Y, Peng N, Chen J, Tang LP, Falk Libby E, Singh AK, Conrath K, Rowe SM. Mutyam V, et al. Am J Respir Cell Mol Biol. 2021 May;64(5):604-616. doi: 10.1165/rcmb.2019-0291OC. Am J Respir Cell Mol Biol. 2021. PMID: 33616476 Free PMC article.

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1. Cystic Fibrosis Mutation Database. Toronto, Ontario, Canada: Hospital for Sick Children; 2021 [accessed 2021 Feb 20]. Available from: http://www.genet.sickkids.on.ca/StatisticsPage.html.
1. Shoshani T, Augarten A, Gazit E, Bashan N, Yahav Y, Rivlin Y, et al. Association of a nonsense mutation (W1282X), the most common mutation in the Ashkenazi Jewish cystic fibrosis patients in Israel, with presentation of severe disease. Am J Hum Genet. 1992;50:222–228. - PMC - PubMed
1. Howard M, Frizzell RA, Bedwell DM. Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations. Nat Med. 1996;2:467–469. - PubMed
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