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Comment
. 2021 Aug;27(8):1177-1178.
doi: 10.1016/j.cmi.2021.02.024. Epub 2021 Mar 8.

Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis - Author's reply

Tarek Kashour  1 , Imad M Tleyjeh  2
Affiliations
Comment

Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis - Author's reply

Tarek Kashour et al. Clin Microbiol Infect. 2021 Aug.
No abstract available

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References

    1. Koeckerling D., Pan D., Barker J. Re: Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis by Tleyjeh et al. Clin Microbiol Infect. 2021;27(8):1175–1176. doi: 10.1016/j.cmi.2021.01.025. - DOI - PMC - PubMed
    1. Tleyjeh I.M., Kashour Z., Damlaj M., Riaz M., Tlayjeh H., Altannir M. Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis. Clin Microbiol Infect. 2020;27(2):215–227. doi: 10.1016/j.cmi.2020.10.036. - DOI - PMC - PubMed
    1. Masiá M., Fernández-González M., Padilla S., Ortega P., García J.A., Agulló V. Gutiérrez, Impact of interleukin-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and antibody responses in patients with COVID-19: a prospective cohort study. EBioMedicine. 2020;60:102999. - PMC - PubMed
    1. Guo C., Li B., Ma H., Wang X., Cai P., Yu Q. Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm. Nat Commun. 2020;11:3924. - PMC - PubMed
    1. Mazzoni A., Salvati L., Maggi L., Capone M., Vanni A., Spinicci M. Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent. J Clin Invest. 2020;130:4694–4703. - PMC - PubMed

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