Renal Involvement in COVID-19: A Review of the Literature
- PMID: 33707958
- PMCID: PMC7943324
- DOI: 10.2147/IDR.S288869
Renal Involvement in COVID-19: A Review of the Literature
Abstract
Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.
Keywords: COVID-19; SARS-CoV-2; acute kidney injury; kidney injury.
© 2021 Migliaccio et al.
Conflict of interest statement
The authors report no conflicts of interest for this work.
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References
-
- World Health Organisation. Novel coronavirus – China; 2020. Available from: https://coronavirus.jhu.edu/map.html.
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