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Case Reports
. 2021 Feb 23:14:2632010X21996338.
doi: 10.1177/2632010X21996338. eCollection 2021 Jan-Dec.

Non-sebaceous Lymphadenoma of the Parotid Gland Mimicking a Pleomorphic Adenoma

Carlos Antonio Morales Morales  1 , Alan Ellison Ramos Mayo  1 , Mauricio Gonzalez-Urquijo  1 , Álvaro Barbosa Quintana  1 , Eduardo Alberto Guzmán Huerta  1
Affiliations
Case Reports

Non-sebaceous Lymphadenoma of the Parotid Gland Mimicking a Pleomorphic Adenoma

Carlos Antonio Morales Morales et al. Clin Pathol. .

Abstract

Non-sebaceous lymphadenoma of the salivary glands is a rare benign lesion, first described in 1991. We present the case of a 54-year-old woman, with a right parotid mass. She underwent right superficial parotidectomy, and histopathology reported a non-sebaceous lymphadenoma due to an encapsulated lesion and multiple non-atypical epithelial inclusions without sebaceous differentiation. The etiology of non-sebaceous lymphadenoma is not yet understood, but it can arise predominantly from the parotid gland. Surgical excision is the treatment of choice.

Keywords: Parotid tumor; non-sebaceous lymphadenoma; parotid.

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Conflict of interest statement

Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Arrow showing the parotid tumor on computed tomographic scan with contrast: (A) axial view and (B) coronal view.
Figure 2.
Figure 2.
Superficial parotidectomy with facial nerve preservation (dashed arrow).
Figure 3.
Figure 3.
(A) Well-circumscribed tumor (arrow) surrounded by normal parotid tissue. (B) Encapsulated lesion, lymphoid background, non-atypical epithelial inclusions, and without sebaceous differentiation (dashed arrow).
Figure 4.
Figure 4.
(A) Cellular background composed of lymphoid tissue and cyst with eosinophilic fluid. (B) Cyst with eosinophilic fluid surrounded by 1 to 3 epithelial cells.
Figure 5.
Figure 5.
Tumor (arrow) and normal parotid tissue (dashed arrow).
See this image and copyright information in PMC

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References

    1. Gallego L, Junquera L, Fresno MF. Non-sebaceous lymphadenoma of the parotid gland: immunohistochemical study and DNA ploidy analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107:555-558. doi:10.1016/j.tripleo.2008.11.018. - DOI - PubMed
    1. Yang S, Chen X, Wang L, Zhang J. Non-sebaceous lymphadenoma of the salivary gland: case report with immunohistochemical investigation. Virchows Arch. 2007;450:595-599. - PubMed
    1. Weiler C, Agaimy A, Zengel P, Zenk J, Kirchner T, Ihrler S. Nonsebaceous lymphadenoma of salivary glands: proposed development from intraparotid lymph nodes and risk of misdiagnosis. Virchows Arch. 2012;460:467-472. - PubMed
    1. Castelino-Prabhu S, Li QK, Ali SZ. Nonsebaceous lymphadenoma of the parotid gland: cytopathologic findings and differential diagnosis. Diagn Cytopathol. 2010;38:137-140. - PubMed
    1. Seethala RR, Stenman G. Update from the 4th edition of the World Health Organization classification of head and neck tumours: tumors of the salivary gland. Head Neck Pathol. 2017;11:55-67. - PMC - PubMed

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