Does tranexamic acid reduce 5-day death due to bleeding in acute gastrointestinal bleed?
- PMID: 33709351
- DOI: 10.1007/s43678-020-00053-z
Does tranexamic acid reduce 5-day death due to bleeding in acute gastrointestinal bleed?
Comment on
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Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.Lancet. 2020 Jun 20;395(10241):1927-1936. doi: 10.1016/S0140-6736(20)30848-5. Lancet. 2020. PMID: 32563378 Free PMC article. Clinical Trial.
References
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- Perner A, Møller MH. Tranexamic acid for severe gastrointestinal bleeding. Lancet (London, England). 2020;395(10241):1885–6. - DOI
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- Bennett C, Klingenberg SL, Langholz E, Gluud LL. Tranexamic acid for upper gastrointestinal bleeding. Cochrane Database Syst Rev. 2014;21:2014(11):CD006640. https://doi.org/10.1002/14651858.CD006640
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- Chornenki NL, Um KJ, Mendoza PA, Samienezhad A, Swarup V, Chai-Adisaksopha C, Siegal DM. Risk of venous and arterial thrombosis in non-surgical patients receiving systemic tranexamic acid: a systematic review and meta-analysis. Thromb Res. 2019;1(179):81–6. - DOI
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