EBNEO Commentary: Red blood cell transfusion thresholds in extremely low birthweight infants

Erin Grace^{1

2

3}, Cathie Hilditch^{2

3}, Amy Keir^{1

2

3}

Affiliations

¹ Department of Neonatal Medicine, Women's and Children's Hospital, North Adelaide, South Australia, Australia.
² SAHMRI Women and Kids, South Australian Health and Medical Institute, North Adelaide, South Australia, Australia.
³ Robinson Research Institute and the Adelaide Medical School, the University of Adelaide, Adelaide, South Australia, Australia.

Comment

Erin Grace et al. Acta Paediatr. 2021 Aug.

. 2021 Aug;110(8):2476-2477.

doi: 10.1111/apa.15818. Epub 2021 Mar 12.

Erin Grace^{1

2

3}, Cathie Hilditch^{2

3}, Amy Keir^{1

2

3}

¹ Department of Neonatal Medicine, Women's and Children's Hospital, North Adelaide, South Australia, Australia.
² SAHMRI Women and Kids, South Australian Health and Medical Institute, North Adelaide, South Australia, Australia.
³ Robinson Research Institute and the Adelaide Medical School, the University of Adelaide, Adelaide, South Australia, Australia.

No abstract available

Comment on

Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants: The ETTNO Randomized Clinical Trial.
Franz AR, Engel C, Bassler D, Rüdiger M, Thome UH, Maier RF, Krägeloh-Mann I, Kron M, Essers J, Bührer C, Rellensmann G, Rossi R, Bittrich HJ, Roll C, Höhn T, Ehrhardt H, Avenarius S, Körner HT, Stein A, Buxmann H, Vochem M, Poets CF; ETTNO Investigators. Franz AR, et al. JAMA. 2020 Aug 11;324(6):560-570. doi: 10.1001/jama.2020.10690. JAMA. 2020. PMID: 32780138 Free PMC article. Clinical Trial.

1. Franz AR, Engel C, Bassler D, et al. Effects of liberal vs restrictive transfusion thresholds on survival and neurocognitive outcomes in extremely low-birth-weight infants: the ETTNO Randomized Clinical Trial. JAMA. 2020;324(6):560-570.
1. Higgins JPT, Churchill R, Chandler J, Cumpston MS. Cochrane Handbook for Systematic Reviews of Interventions Version 5.2.0 Cochrane; Updated June 2017.
1. Kirpalani H., Bell E. F., Hintz S. R., et al. Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. New England Journal of Medicine. 2020;383(27):2639-2651. https://doi.org/10.1056/nejmoa2020248
1. Andersen CC, Keir AK, Kirpalani HM, Stark MJ. Anaemia in the premature infant and red blood cell transfusion: new approaches to an age-old problem. Current Treatment Options in Pediatrics. 2015;1(3):191-201.