Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Apr 1;40(4):e159-e161.
doi: 10.1097/INF.0000000000003050.

Mistaken MIS-C: A Case Series of Bacterial Enteritis Mimicking MIS-C

Zephyr D Dworsky  1   2 , Jordan E Roberts  3   4 , Mary Beth F Son  3   4 , Adriana H Tremoulet  1   2 , Jane W Newburger  3   5 , Jane C Burns  1   2
Affiliations
Case Reports

Mistaken MIS-C: A Case Series of Bacterial Enteritis Mimicking MIS-C

Zephyr D Dworsky et al. Pediatr Infect Dis J. .

Abstract

Multisystem inflammatory syndrome in children following severe acute respiratory syndrome coronavirus 2 infection is characterized by fever, elevated inflammatory markers, and multisystem organ involvement. Presentations are variable but often include gastrointestinal symptoms. We describe 5 children with fever and gastrointestinal symptoms initially concerning for multisystem inflammatory syndrome in children who were ultimately diagnosed with bacterial enteritis, highlighting the diagnostic challenges presented by the severe acute respiratory syndrome coronavirus 2 pandemic.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest for any authors.

References

    1. Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet Lond Engl. 2020;395(10237):1607–1608. doi:10.1016/S0140-6736(20)31094-1 - DOI - PMC - PubMed
    1. Verdoni L, Mazza A, Gervasoni A, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet Lond Engl. 2020;395(10239):1771–1778. doi:10.1016/S0140-6736(20)31103-X - DOI - PMC - PubMed
    1. CDCHAN-00432, May 14, 2020. Multisystem Inflammatory Syndrome in Children(MIS-C) Associated with Coronavirus Disease 2019 (COVID-19). Available at: https://emergency.cdc.gov/han/2020/han00432.asp. Accessed November 28, 2020.
    1. Whittaker E, Bamford A, Kenny J, et al. Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2. JAMA. 2020;324(3):259–269. doi:10.1001/jama.2020.10369 - DOI - PMC - PubMed
    1. Miller J, Cantor A, Zachariah P, Ahn D, Martinez M, Margolis KG. Gastrointestinal Symptoms as a Major Presentation Component of a Novel Multisystem Inflammatory Syndrome in Children That Is Related to Coronavirus Disease 2019: A Single Center Experience of 44 Cases. Gastroenterology. 2020;159(4):1571–1574.e2. doi:10.1053/j.gastro.2020.05.079 - DOI - PMC - PubMed

Publication types