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Comparative Study
. 1988;10(1):27-30.

[Histamine-receptor sensitivity of lymphocytes in patients with early and advanced stage breast cancer]

[Article in Russian]
D D Kharkevich, E B Polevaia
  • PMID: 3371246
Comparative Study

[Histamine-receptor sensitivity of lymphocytes in patients with early and advanced stage breast cancer]

[Article in Russian]
D D Kharkevich et al. Eksp Onkol. 1988.

Abstract

It is established that histamine in the concentration of 10(-4)-10(-5) M possesses an inhibitory effect in the lymphocyte adherence inhibition test in patients with breast cancer. Using specific antagonists (H1-blocker dimedrol and H2-blocker cimetidine) it is shown that the revealed histaminergic suppression of the lymphocyte adherence inhibition is mediated through the stimulating influence of histamine on H2-receptors.

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