Effects of Bariatric Surgery on Heart Rhythm Disorders: a Systematic Review and Meta-Analysis

Elijah E Sanches¹, Besir Topal², Frank W de Jongh³, Eylem Cagiltay⁴, Alper Celik⁵, Magnus Sundbom⁶, Rui Ribeiro⁷, Chetan Parmar⁸, Surendra Ugale⁹, Kamal Mahawar¹⁰, Marc P Buise¹¹, Lukas R Dekker¹², Dharmanand Ramnarain¹³, Sjaak Pouwels¹⁴

Affiliations

¹ Department of Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
² Department of Cardiothoracic Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
³ Department of Plastic Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
⁴ Department of Endocrinology and Metabolic Diseases, University of Health Sciences Turkey, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
⁵ Metabolic Surgery Clinic, Sisli, Istanbul, Turkey.
⁶ Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
⁷ Centro Multidisciplinar da Doença Metabólica, Clínica de Santo António, Reboleira, Lisbon, Portugal.
⁸ Department of Surgery, Whittington Hospital, London, United Kingdom.
⁹ Bariatric & Metabolic Surgery Clinic, Virinchi Hospitals, Hyderabad, India.
¹⁰ Bariatric Unit, Sunderland Royal Hospital, Sunderland, United Kingdom.
¹¹ Department of Anesthesiology, Intensive Care and Pain Medicine, Catharina Hospital, Eindhoven, The Netherlands.
¹² Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands.
¹³ Department of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, P.O. Box 9051, 5000 LC, Tilburg, The Netherlands.
¹⁴ Department of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, P.O. Box 9051, 5000 LC, Tilburg, The Netherlands. Sjaakpwls@gmail.com.

PMID: 33712936
DOI: 10.1007/s11695-021-05314-z

Meta-Analysis

Effects of Bariatric Surgery on Heart Rhythm Disorders: a Systematic Review and Meta-Analysis

Elijah E Sanches et al. Obes Surg. 2021 May.

. 2021 May;31(5):2278-2290.

doi: 10.1007/s11695-021-05314-z. Epub 2021 Mar 13.

Authors

Affiliations

¹ Department of Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
² Department of Cardiothoracic Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
³ Department of Plastic Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
⁴ Department of Endocrinology and Metabolic Diseases, University of Health Sciences Turkey, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
⁵ Metabolic Surgery Clinic, Sisli, Istanbul, Turkey.
⁶ Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
⁷ Centro Multidisciplinar da Doença Metabólica, Clínica de Santo António, Reboleira, Lisbon, Portugal.
⁸ Department of Surgery, Whittington Hospital, London, United Kingdom.
⁹ Bariatric & Metabolic Surgery Clinic, Virinchi Hospitals, Hyderabad, India.
¹⁰ Bariatric Unit, Sunderland Royal Hospital, Sunderland, United Kingdom.
¹¹ Department of Anesthesiology, Intensive Care and Pain Medicine, Catharina Hospital, Eindhoven, The Netherlands.
¹² Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands.
¹³ Department of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, P.O. Box 9051, 5000 LC, Tilburg, The Netherlands.
¹⁴ Department of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, P.O. Box 9051, 5000 LC, Tilburg, The Netherlands. Sjaakpwls@gmail.com.

PMID: 33712936
DOI: 10.1007/s11695-021-05314-z

Abstract

The aim of this systematic review is to provide an overview of the literature on the effects of bariatric surgery on obesity-associated electrocardiogram (ECG) abnormalities and cardiac arrhythmias. Fourteen studies were included with a methodological quality ranging from poor to good. Majority of the studies showed a significant decrease of QT interval and related measures after bariatric surgery. Seven studies were included in the meta-analysis on effects of bariatric surgery on QTc interval and a significant decrease in QTc interval of - 33.6 ms, 95%CI [- 49.8 to - 17.4] was seen. Bariatric surgery results in significant decrease in QTc interval and P-wave dispersion, i.e., a normalization of initial pathology. The effects on atrial fibrillation are conflicting and not yet fully understood.

Keywords: Atrial fibrillation; Bariatric surgery; Heart rhythm disorders; Metabolic surgery; Obesity.

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Comment in

Response to: "QT Interval Shortening After Bariatric Surgery-Mind the Heart Rate Correction Equation".
Pouwels S, Sanches EE, Topal B, de Jongh FW, Cagiltay E, Celik A, Sundbom M, Ribeiro R, Parmar C, Ugale S, Mahawar K, Buise MP, Dekker LR, Ramnarain D. Pouwels S, et al. Obes Surg. 2021 Oct;31(10):4638-4639. doi: 10.1007/s11695-021-05503-w. Epub 2021 Jun 1. Obes Surg. 2021. PMID: 34061301 No abstract available.
QT Interval Shortening After Bariatric Surgery: Mind the Heart Rate Correction Equation.
Schultes B, Grasser EK, Ernst B. Schultes B, et al. Obes Surg. 2021 Oct;31(10):4637. doi: 10.1007/s11695-021-05502-x. Epub 2021 Jun 3. Obes Surg. 2021. PMID: 34081272 No abstract available.

References

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Effects of Bariatric Surgery on Heart Rhythm Disorders: a Systematic Review and Meta-Analysis

Affiliations

Effects of Bariatric Surgery on Heart Rhythm Disorders: a Systematic Review and Meta-Analysis

Authors

Affiliations

Abstract

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References

Publication types

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LinkOut - more resources

Full Text Sources

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Medical