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Review
. 2021 Feb 26:11:610514.
doi: 10.3389/fonc.2021.610514. eCollection 2021.

Volatile Anesthetics Regulate Anti-Cancer Relevant Signaling

Jiaqiang Wang  1 , Chien-Shan Cheng  2   3 , Yan Lu  4 , Shen Sun  1 , Shaoqiang Huang  1
Affiliations
Review

Volatile Anesthetics Regulate Anti-Cancer Relevant Signaling

Jiaqiang Wang et al. Front Oncol. .

Abstract

Volatile anesthetics are widely used inhalation anesthetics in clinical anesthesia. In recent years, the regulation of anti-cancer relevant signaling of volatile anesthetics has drawn the attention of investigators. However, their underlying mechanism remains unclear. This review summarizes the research progress on the regulation of anti-cancer relevant signaling of volatile anesthetics, including sevoflurane, desflurane, xenon, isoflurane, and halothane in vitro, in vivo, and clinical studies. The present review article aims to provide a general overview of regulation of anti-cancer relevant signaling and explore potential underlying molecular mechanisms of volatile anesthetics. It may promote promising insights of guiding clinical anesthesia procedure and instructing enhance recovery after surgery (ERAS) with latent benefits.

Keywords: anti-cancer; inhalation anesthesia; mechanism; volatile anesthesia; volatile anesthetics.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Mechanisms of regulation of anti-cancer relevant signaling of volatile anesthetics.
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