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. 2021 Feb 25:9:612539.
doi: 10.3389/fcell.2021.612539. eCollection 2021.

What Is the Right Mechanical Readout for Understanding the Mechanobiology of the Immune Response?

Marco Fritzsche  1   2
Affiliations

What Is the Right Mechanical Readout for Understanding the Mechanobiology of the Immune Response?

Marco Fritzsche. Front Cell Dev Biol. .
No abstract available

Keywords: biophysics; dynamics; feedback; mechanical force; mechanical properties; mechanics; stiffness; tension.

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Conflict of interest statement

The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handling editor declared a past co-authorship with one of the authors MF.

Figures

Figure 1
Figure 1
(A) Schematic of the T cell (left) and Target cell (right) interplay. (B) Explanation of the mechanical metric tension with tensile stress σ in units of N/m2 and tensile strain ε being dimenionless, and shear with shear stress τ in N/m2, as well as the elasticity with Youngst modulus E, which equals the ratio of stress over strain. The stiffness of a material is given by EA/l. (C) Cells are elastic, viscous, or visco-elastic.
See this image and copyright information in PMC

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