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. 2021 Feb 24:8:636904.
doi: 10.3389/fmed.2021.636904. eCollection 2021.

Itch Matrixes

Peyman Najafi  1   2 , Laurent Misery  1   3 , Jean-Luc Carré  1 , Douraied Ben Salem  4   5 , Olivier Dufor  1   6
Affiliations

Itch Matrixes

Peyman Najafi et al. Front Med (Lausanne). .
No abstract available

Keywords: brain; imaging; itch; matrix; pain.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The itch matrix categorized into three itch matrixes. First itch matrix consisted of primary and secondary sensorimotor cortex (SI and SII, respectively), the parietal/central operculum, and the posterior insular cortex (pIC) (here presented in brown, this matrix is also presented in Figure 2A). The second itch matrix consisting of anterior singular cortex (ACC), anterior part of the middle cingulate cortex (aMCC), anterior part of the insular cortex (aIC), amygdala, striatum and hippocampus (here presented in blue, this matrix is also presented in Figure 2B). The third matrix contains prefrontal cortex, posterior part of the middle cingulate cortex (pMCC), and posterior cingulate cortex (PCC) (here presented in red, this matrix is also presented in Figure 2C).
Figure 2
Figure 2
Proposals for itch matrixes (X,Y,Z denotes the location of the corresponding slice in Montreal Neurological Institute (MNI) coordinate system). (A) Elements of the first matrix contributing to encoding of the recognition, localization, and intensity of itch. Primary sensorimotor cortex is presented in Blue, parietal operculum in Green, and posterior insular cortex in Red (Regions have been extracted from Automated Anatomical Labeling and Harvard-Oxford atlases). (B) The second matrix itch processing matrix consenting of anterior cingulate cortex (Blue), anterior insular cortex (Red), amygdala (Green) and hippocampus (Violet). This matrix is in charge of affective and motivational aspects of itch. (C) The third matrix consists of frontal cortex (Blue), middle cingulate cortex (Red), and posterior cingulate cortex (Green), and it is involved in the interpretation of the cognitive meaning of itch.
See this image and copyright information in PMC

References

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