Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Feb 15;4(2):118-121.
doi: 10.1002/iju5.12259. eCollection 2021 Mar.

Rapid recurrence of squamous cell carcinoma at a lymphocele after nephroureterectomy: A rare case report

Kosuke Ogawa  1 , Yousuke Shimizu  1 , Shoko Uketa  1 , Noriaki Utsunomiya  1 , Satsuki Asai  2 , Misa Ishihara  2 , Kimio Hashimoto  2 , Sojun Kanamaru  1
Affiliations
Case Reports

Rapid recurrence of squamous cell carcinoma at a lymphocele after nephroureterectomy: A rare case report

Kosuke Ogawa et al. IJU Case Rep. .

Abstract

Introduction: Lymphoceles are sometimes formed after pelvic lymph node dissection. However, recurrence at lymphoceles has not been reported previously. Here, we report a case of rapid prognosis of the recurrence at a lymphocele after nephroureterectomy.

Case presentation: A 78-year-old man underwent retroperitoneoscopic radical nephroureterectomy with pelvic lymphadenectomy for left ureteral urothelial carcinoma. The histopathological diagnosis was high-grade invasive urothelial carcinoma with squamous differentiation. Follow-up computed tomography at 3 months postoperatively showed a lymphocele with a small solid component, in the left pelvic region. At 7 months postoperatively, he presented with severe fatigue, and computed tomography showed a solid tumor had replaced the lymphocele. Computed tomography-guided biopsy was performed and histopathological diagnosis was squamous cell carcinoma.

Conclusion: This report provides support for possible recurrence at the lymphocele after nephroureterectomy. If lymphocele occurs after surgery for malignant disease, it is recommended to follow up with the possibility of recurrence in the lymphatic cysts in mind.

Keywords: lymphocele; metastasis; squamous differentiation; ureteral cancer; urothelial carcinoma.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
(a) There are invasive urothelial carcinoma, mainly composed of well‐differentiated SCC (hematoxylin‐eosin, bar = 100 μm). (b) There are well‐differentiated SCC and the histopathological findings are similar to those of ureteral cancer (a) (hematoxylin‐eosin, bar = 200 μm).
Fig. 2
Fig. 2
The postoperative 3‐month CT scan (a: axial view, b: coronal view) showed a lymphocele with a small solid component in the wall, in the left pelvic region. The coronal view showed the solid component area was distant from the UVJ. The postoperative 7‐month CT scan (c: axial view, d: coronal view) showed a solid mass had replaced the lymphocele in the left pelvic region.
Fig. 3
Fig. 3
MRI showed that the mass with arrow pointing was isointense on (a) T1‐ and (b) T2‐weighted imaging and hyperintense on (c) diffusion‐weighted imaging.
See this image and copyright information in PMC

References

    1. Roupret M, Babjuk M, Comperat E et al. European guidelines on upper tract urothelial carcinomas: 2013 update. Eur. Urol. 2013; 63: 1059–71. - PubMed
    1. Munoz JJ, Ellison LM. Upper tract urothelial neoplasms: incidence and survival during the last 2 decades. J. Urol. 2000; 164: 1523–5. - PubMed
    1. Joung JY, Lim J, Oh CM et al. Current trends in the incidence and survival rate of urological cancers in Korea. Cancer Res. Treat. 2017; 49: 607–15. - PMC - PubMed
    1. Rink M, Robinson BD, Green DA et al. Impact of histological variants on clinical outcomes of patients with upper urinary tract urothelial carcinoma. J. Urol. 2012; 188: 398–404. - PubMed
    1. Liu Y, Bui MM, Xu B. Urothelial carcinoma with squamous differentiation is associated with high tumor stage and pelvic lymph‐node metastasis. Cancer Control 2017; 24: 78–82. - PubMed

Publication types

LinkOut - more resources