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1 Department of Translational Medicine, University of Ferrara, Via Aldo Moro 8, 44124, Cona, Ferrara, Italy.
2 Department of Specialistic Medicine, Division of Cardiology, Santa Maria della Misericordia Hospital, Rovigo General Hospital, Viale tre Martiri 140, Rovigo 45100, Italy.
1 Department of Translational Medicine, University of Ferrara, Via Aldo Moro 8, 44124, Cona, Ferrara, Italy.
2 Department of Specialistic Medicine, Division of Cardiology, Santa Maria della Misericordia Hospital, Rovigo General Hospital, Viale tre Martiri 140, Rovigo 45100, Italy.
Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) has been associated with coagulation dysfunction which predisposes patients to an increased risk of both venous and arterial thromboembolism, increasing the short-term morbidity and mortality. Current data evidenced that the rate of post-discharge thrombotic events in COVID-19 patients is lower compared to that observed during hospitalization. Rather than 'true thrombotic events', these complications seem more probably 'immunothrombosis' consequent to the recent infection. Unfortunately, the absence of data from randomized controlled trials, large prospective cohorts and ambulatory COVID-19 patients, left unresolved the question regarding the need of post-discharge thromboprophylaxis due to the absence of strong-level recommendations.
Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost 2020; 18:844–7.
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-
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Malas MB, Naazie IN, Elsayed N, Mathlouthi A, Marmor R, Clary B. Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: a systematic review and meta-analysis. E Clin Med 2020; 29:100639.
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Chaudhary R, Bliden KP, Kreutz RP, Jeong YH, Tantry US, Levy JH, et al. Race-related disparities in COVID-19 thrombotic outcomes: beyond social and economic explanations. E Clin Med 2020; 29:100647.
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Roncon L, Zuin M, Barco S, Valerio L, Zuliani G, Zonzin P, et al. Incidence of acute pulmonary embolism in COVID-19 patients: systematic review and meta-analysis. Eur J Intern Med 2020; 82:29–37.
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