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Comment
. 2021 Mar 16:10:e67417.
doi: 10.7554/eLife.67417.

Should I stay or should I go?

Affiliations
Comment

Should I stay or should I go?

Mirjam Kretzschmar et al. Elife. .

Abstract

Analysing the characteristics of the SARS-CoV-2 virus makes it possible to estimate the length of quarantine that reduces the impact on society and the economy, while minimising infections.

Keywords: COVID-19; SARS-CoV-2; contact tracing; epidemic containment; epidemiology; global health; human; quarantine.

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Conflict of interest statement

MK, JM No competing interests declared

Figures

Figure 1.
Figure 1.. Costs versus benefits of quarantine depending on time.
The costs of quarantine (yellow bars and arrow) increase steadily with time, while the benefits (green arrow) – measured as number of onward transmissions (red bars) prevented – increase steeply at first, and then flatten. Ashcroft et al. estimate that balance between costs and benefits – known as the utility (blue arrow) – increases at first, reaching a peak after 6–8 days, and then decreases.

Comment on

References

    1. Ashcroft P, Lehtinen S, Angst DC, Low N, Bonhoeffer S. Quantifying the impact of quarantine duration on COVID-19 transmission. eLife. 2021;10:e63704. doi: 10.7554/eLife.63704. - DOI - PMC - PubMed
    1. CDC Options to reduce quarantine for contacts of persons with SARS-CoV-2 infection using symptom monitoring and diagnostic testing. [March 1, 2021];2021 https://www.cdc.gov/coronavirus/2019-ncov/more/scientific-brief-options-... - PubMed
    1. Denysiuk R, Silva CJ, Torres DFM. Multiobjective approach to optimal control for a tuberculosis model. Optimization Methods and Software. 2015;30:893–910. doi: 10.1080/10556788.2014.994704. - DOI
    1. ECDC Contact tracing: public health management of persons, including healthcare workers, who have had contact with COVID-19 cases in the European Union – third update. [March 1, 2021];2020 https://www.ecdc.europa.eu/en/covid-19-contact-tracing-public-health-man...
    1. Quilty BJ, Clifford S, Hellewell J, Russell TW, Kucharski AJ, Flasche S, Edmunds WJ, Centre for the Mathematical Modelling of Infectious Diseases COVID-19 working group Quarantine and testing strategies in contact tracing for SARS-CoV-2: a modelling study. The Lancet Public Health. 2021;6:e175–e183. doi: 10.1016/S2468-2667(20)30308-X. - DOI - PMC - PubMed