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Editorial
. 2021 Aug;74(2):543-546.
doi: 10.1002/hep.31807. Epub 2021 Jun 11.

Ten Thousand Points of Light: Heterogeneity Among the Stars of NASH Fibrosis

James Carter  1 , Shuang Wang, Scott L Friedman
Affiliations
Editorial

Ten Thousand Points of Light: Heterogeneity Among the Stars of NASH Fibrosis

James Carter et al. Hepatology. 2021 Aug.
No abstract available

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Figures

FIG 1.
FIG 1.
Identification of hepatic stellate cell subpopulations in the Alms1−/− and Western diet NASH model. Pooled analysis of HSCs enriched from control, NASH, and recovering mice reveals substantial HSC heterogeneity in healthy and diseased livers. Tables list the top genes expressed by the indicated HSC clusters (full lists not shown). Abbreviations: HSC, hepatic stellate cell; NASH, non-alcoholic steatohepatitis.
See this image and copyright information in PMC

Comment on

  • Heterogeneity of HSCs in a Mouse Model of NASH.
    Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. Rosenthal SB, et al. Hepatology. 2021 Aug;74(2):667-685. doi: 10.1002/hep.31743. Epub 2021 Aug 10. Hepatology. 2021. PMID: 33550587 Free PMC article.

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    1. Rosenthal S, Liu X, Ganguly S, Dhar D, Pasillas M, Ricciardelli E, Li R, et al.Heterogeneity of hepatic stellate cells in a mouse model of non-alcoholic steatohepatitis (NASH). Hepatology 2021. - PMC - PubMed