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. 2021 Mar 8;25(3):140-56.
doi: 10.29252/ibj.25.3.140. Online ahead of print.

Immunotherapy for Breast Cancer Treatment

Miganoosh Simonian  1 , Mozhan Haji Ghaffari  1 , Babak Negahdari  1
Affiliations

Immunotherapy for Breast Cancer Treatment

Miganoosh Simonian et al. Iran Biomed J. .

Abstract

Breast cancer, as a heterogeneous disease, includes a wide range of pathological and clinical behaviors. Current treatment protocols, including radiotherapy, chemotherapy, and hormone replacement therapy, are mainly associated with poor response and high rate of recurrence. Therefore, more efforts are needed to develop alternative therapies for this type of cancer. Immunotherapy, as a novel strategy in cancer treatment, has a potential in treating breast cancer patients. Although breast cancer has long been considered problematic to treat with immunotherapy, as it is immunologically "cold," numerous newer preclinical and clinical reports now recommend that immunotherapy has the capability to treat breast cancer patients. In this review, we highlight the different immunotherapy strategies in breast cancer treatment.

Keywords: Antibodies; Breast cancer; Immunotherapy.

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Figures

Fig. 1
Fig. 1
Four different immunotherapy strategies in breast cancer
See this image and copyright information in PMC

References

    1. Al Tamimi DM, Shawarby MA, Ahmed A, Hassan AK, AlOdaini AA. Protein expression profile and prevalence pattern of the molecular classes of breast cancer-a Saudi population based study. BMC cancer. 2010;10(1) Article number 223. - PMC - PubMed
    1. Stewart BW, Wild CP. France: International agency for research on cancer world health organization (IARC) 2014. World Cancer Report 2014.
    1. Pisani P, Parkin D, Ferlay J. Estimates of the worldwide mortality from eighteen major cancers in 1985 Implications for prevention and projections of future burden. International journal of cancer. 1993;55(6):891–903. - PubMed
    1. Parkin DM. France: International agency for research on cancer world health organization (IARC) 1997. Cancer Incidence in Five Continents.
    1. Taghavi A, Fazeli Z, Vahedi M, Baghestani AR, Pourhoseingholi A, Barzegar F, Pourhoseingholi MA. Increased trend of breast cancer mortality in Iran. Asian pacific journal of cancer prevention. 2012;13(1):367–370. - PubMed

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