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Review
. 2021 Apr;46(4):1519-1529.
doi: 10.1007/s00261-021-02998-w. Epub 2021 Mar 16.

Comprehensive review of imaging features of sex cord-stromal tumors of the ovary

Sanaz Javadi  1 , Dhakshina M Ganeshan  2 , Corey T Jensen  2 , Revathy B Iyer  2 , Priya R Bhosale  2
Affiliations
Review

Comprehensive review of imaging features of sex cord-stromal tumors of the ovary

Sanaz Javadi et al. Abdom Radiol (NY). 2021 Apr.

Abstract

Sex cord-stromal tumors of the ovary (SCST) are uncommon ovarian tumors arising from sex cord and/or stromal cells of the ovaries. They may be nonfunctional and asymptomatic or functional presenting with hyperestrogenic, hyperandrogenic or cushingoid symptoms. They present in a wide age group of women, mostly in early stages and follow a nonaggressive clinical course after surgical resection. They differ from more prevalent epithelial ovarian tumors which tend to present in older women in advanced stages with poor prognosis. Some of SCSTs are associated with clinical syndromes. We will review imaging features on ultrasound, computed tomography and magnetic resonance imaging, epidemiology and clinical presentations of these tumors.

Keywords: Fibroma; Granulosa cell tumor; Sertoli cell tumor; Sex cord-stromal tumors of the ovary; Thecoma.

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References

    1. Haroon S, Zia A, Idrees R, et al. (2013) Clinicopathological spectrum of ovarian sex cord-stromal tumors; 20 years’ retrospective study in a developing country. Journal of ovarian research 6(1):87. https://doi.org/10.1186/1757-2215-6-87 - DOI - PubMed - PMC
    1. Quirk JT, Natarajan N (2005) Ovarian cancer incidence in the United States, 1992-1999. Gynecologic oncology 97(2):519–523. https://doi.org/10.1016/j.ygyno.2005.02.007 - DOI - PubMed
    1. Kurman RJ, Carcangiu ML, Herrington CS, Young RH (2014) Classification of tumours of the ovary. In: WHO classification of tumours. vol 6, 4th edn. IARC, Lyon, pp 44–56
    1. Pratt J (2004) Pathology of the ovary, 1st edn. Philadelphia: Sounders
    1. Levin G, Zigron R, Haj-Yahya R, Matan LS, Rottenstreich A (2018) Granulosa cell tumor of ovary: A systematic review of recent evidence. European journal of obstetrics, gynecology, and reproductive biology 225:57–61. https://doi.org/10.1016/j.ejogrb.2018.04.002 - DOI - PubMed

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