Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun;31(6):2723-2728.
doi: 10.1007/s11695-021-05329-6. Epub 2021 Mar 16.

Vitamin D in the Preoperative and Postoperative Periods of Bariatric Surgery

Eryka M Dos Santos  1 , Denise S C de Lima  2 , Bruna M Padilha  2 , Poliana C Cabral  2 , Luciana C P do Nascimento  3 , Pedro H F Feitosa  4 , Álvaro A B Ferraz  4
Affiliations

Vitamin D in the Preoperative and Postoperative Periods of Bariatric Surgery

Eryka M Dos Santos et al. Obes Surg. 2021 Jun.

Abstract

Objective: To evaluate the evolution of vitamin D levels (25OHD) in patients submitted to bariatric surgery.

Methods: Retrospective study, conducted with patients submitted to bariatric surgery between 2013 and 2018, in a city in the Northeast of Brazil. The variations of 25OHD, weight, body mass index (BMI), and total lymphocyte count were analyzed and compared for preoperative and postoperative periods of 6 and 12 months. Vitamin D levels below 30ng/mL were considered insufficient. Analysis of variance (ANOVA) was used for repeated measures, followed by Bonferroni post hoc test. To identify variables related to vitamin D, Pearson's correlation test and linear regression analysis were used. A significance level of 5% (p <0.05) was adopted.

Results: A total of 646 patients were evaluated, with a mean age of 41.3 ± 10.8 years. Most of the patients were female (75%) and had 25OHD insufficiency in the preoperative period (79.1%). It was found that in the postoperative period there was an increase in vitamin D levels. Linear regression showed that the variation in vitamin D is negatively influenced by BMI in the preoperative period (β = -0.20; p = 0.02) and by BMI (β = -0.38; p <0.001) and by age (β = -0.08; p = 0.02) in the 6-month postoperative period.

Conclusion: There was an increase in vitamin D levels in the postoperative period. BMI proved to be a negative factor for obtaining adequate levels of vitamin D in the preoperative period and in the 6-month postoperative period.

Keywords: Avitaminosis; Bariatric surgery; Obesity; Postoperative period; Preoperative period.

PubMed Disclaimer

References

    1. Aridi HD, Alami RS, Fouani T, et al. Prevalence of vitamin D deficiency in adults presenting for bariatric surgery in Lebanon. Surg Obes Relat Dis. 2016;12(2):405–11. - DOI
    1. Brasil, Vigitel. Vigilância de fatores de risco e proteção para doenças crônicas por inquérito telefônico: estimativas sobre frequência e distribuição sociodemográfica de fatores de risco e proteção para doenças crônicas nas capitais dos 26 estados brasileiros e no Distrito Federal em 2018. Brasília: MS, 2019
    1. Samuel L, Borrell LN. The effect of body mass index on adequacy of serum 25-hydroxyvitamin D levels in US adults: the National Health and Nutrition Examination Survey 2001 to 2006. Ann Epidemiol. 2014;24(10):781–4. - DOI
    1. Lanzarini E, Nogués X, Goday A, et al. High-dose vitamin D supplementation is necessary after bariatric surgery: a prospective 2-year follow-up study. Obes Surg. 2015;25(9):1633–8. - DOI
    1. Chakhtoura MT, Nakhoul NN, Shawwa K, et al. Hypovitaminosis D in bariatric surgery: a systematic review of observational studies. Metabolism. 2016;65(4):574–85. - DOI

LinkOut - more resources