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Case Reports
. 2021 Feb 3;13(2):e13096.
doi: 10.7759/cureus.13096.

Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature

Mostafa Meshref  1 , Hessa A Alshammari  2 , Shiamaa M Khairat  3 , Roohi Khan  2 , Imran Khan  2
Affiliations
Case Reports

Guillain-Barre Syndrome Associated With COVID-19 Infection: A Case Report With Review of Literature

Mostafa Meshref et al. Cureus. .

Abstract

COVID-19 has become a pandemic. It affects multiple systems of the body including the nervous system. It invades the nervous systems through multiple routes - either olfactory tract, bloodstream (by binding to endothelial receptors) or via ACE-2 receptors in the brain. We report a case of Guillain-Barré syndrome (GBS) variant (acute motor axonal neuropathy (AMAN type)) associated with COVID-19 infection with positive polymerase chain reaction (PCR) test for COVID-19 and positive contact history with infected family member. GBS and its variants like AMAN can occur due to COVID-19 infection through its immune-mediated effects. Diagnosis of GBS should depend on the clinical and supportive criteria. The treatment should be started early to prevent progression and disease co-morbidities.

Keywords: acute motor axonal neuropathy; covid-19; guillain-barré syndrome.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. MRI cervical spine without contrast
Figure 2
Figure 2. MRI brain
Figure 3
Figure 3. X-ray chest
See this image and copyright information in PMC

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