Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Mar 5;8(3):ofab041.
doi: 10.1093/ofid/ofab041. eCollection 2021 Mar.

Peripherally Inserted Central Catheter-Associated Nocardia nova Endocarditis in a Patient Receiving Intravenous Antibiotics for Chronic Lyme Disease

Aji B Njie  1 , Michael Mitchell  1 , Read Pukkila-Worley  1
Affiliations
Case Reports

Peripherally Inserted Central Catheter-Associated Nocardia nova Endocarditis in a Patient Receiving Intravenous Antibiotics for Chronic Lyme Disease

Aji B Njie et al. Open Forum Infect Dis. .

Abstract

Long-term antibiotics are not effective for the therapy of patients with persistent symptoms and a history of Lyme disease. However, some clinicians still prescribe these therapies. We present a case of peripherally inserted central catheter-associated Nocardia nova endocarditis in a patient who had been receiving intravenous antibiotics for the management of chronic Lyme disease. This case highlights an important risk associated with the unscientific use of indwelling peripheral catheters and intravenous antibiotics for the management of such patients.

Keywords: Nocardia nova endocarditis; Peripherally Inserted Central Catheter-Associated infection; Persistent symptoms and a diagnosis of Lyme Disease.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Computed tomography of the patient’s chest. Multiple scattered nodules in the periphery of the lungs (arrow) were identified.
Figure 2.
Figure 2.
Gram stain of the organism growing in blood culture.
Figure 3.
Figure 3.
A modified acid-fast bacilli stain of the organism growing in blood culture.
See this image and copyright information in PMC

References

    1. Klempner MS, Hu LT, Evans J, et al. Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease. N Engl J Med 2001; 345:85–92. - PubMed
    1. Kaplan RF, Trevino RP, Johnson GM, et al. Cognitive function in post-treatment Lyme disease: do additional antibiotics help? Neurology 2003; 60:1916–22. - PubMed
    1. Berende A, ter Hofstede HJ, Vos FJ, et al. Randomized trial of longer-term therapy for symptoms attributed to Lyme disease. N Engl J Med 2016; 374:1209–20. - PubMed
    1. Krupp LB, Hyman LG, Grimson R, et al. Study and treatment of post Lyme disease (STOP-LD): a randomized double masked clinical trial. Neurology 2003; 60:1923–30. - PubMed
    1. Marzec NS, Nelson C, Waldron PR, et al. Serious bacterial infections acquired during treatment of patients given a diagnosis of chronic Lyme disease - United States. MMWR Morb Mortal Wkly Rep 2017; 66:607–9. - PMC - PubMed

Publication types