Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 Jun 1;23(6):874-876.
doi: 10.1093/neuonc/noab066.

Pediatric ependymomas: destined to recur?

Timothy A Ritzmann  1 , John-Paul Kilday  2 , Richard G Grundy  1
Affiliations
Editorial

Pediatric ependymomas: destined to recur?

Timothy A Ritzmann et al. Neuro Oncol. .
No abstract available

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
(A) Improvement in survival of childhood ependymoma from 1960 to 2015 in the UK. Based on 347 retrospectively analyzed UK cases—unpublished data associated with the Ritzmann et al.’s 2020 study. (B) Proposed structure for a relapsed ependymoma clinical trial allowing the comparison of craniospinal and focal radiotherapy. Abbreviations: CSI, craniospinal irradiation; M0, no metastatic disease; RT, radiotherapy.
See this image and copyright information in PMC

Comment on

References

    1. Marinoff AE, Ma C, Guo D, et al. . Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival. J Neurooncol. 2017;135(1):201–211. - PMC - PubMed
    1. Ritzmann TA, Rogers HA, Paine SML, et al. . A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups. Pediatr Blood Cancer. 2020;67(9):e28426. - PubMed
    1. Zacharoulis S, Ashley S, Moreno L, Gentet JC, Massimino M, Frappaz D. Treatment and outcome of children with relapsed ependymoma: a multi-institutional retrospective analysis. Childs Nerv Syst. 2010;26(7):905–911. - PubMed
    1. Donovan LK, Delaidelli A, Joseph SK, et al. . Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma. Nat Med. 2020;26(5):720–731. - PMC - PubMed
    1. Pajtler KW, Witt H, Sill M, et al. . Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups. Cancer Cell. 2015;27(5):728–743. - PMC - PubMed