Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Oct;74(10):4508-10.
doi: 10.1073/pnas.74.10.4508.

Helper factor(s) for growth of adeno-associated virus in cells transformed by adenovirus 12

H Handa, K Shiroki, H Shimojo

Helper factor(s) for growth of adeno-associated virus in cells transformed by adenovirus 12

H Handa et al. Proc Natl Acad Sci U S A. 1977 Oct.

Abstract

Evidence is presented that a helper factor(s) for growth of adeno-associated virus (AAV) is present in cells transformed by adenovirus type 12 (Ad12). The growth of AAV was observed in heterokaryons formed by fusion of human KB and Ad12-transformed rodent cells by using ultraviolet-inactivated Sendai virus without coinfection of cells with adenovirus. The presence of the helper factor(s) for AAV growth in rat cells transformed by the EcoRI-C fragment or the HindIII-G fragment of Ad12DNA suggests that the helper factor(s) induced by infection with adenovirus is the Ad12-specific T antigen.

PubMed Disclaimer

References

    1. Science. 1965 Aug 13;149(3685):754-6 - PubMed
    1. Exp Cell Res. 1962 Feb;26:98-107 - PubMed
    1. J Gen Virol. 1975 Nov;29(2):239-42 - PubMed
    1. J Virol. 1977 Jun;22(3):679-93 - PubMed
    1. Virology. 1977 Oct 15;82(2):462-71 - PubMed

LinkOut - more resources