The authors reply

Youssef Bennis^{1

2}, Marc E De Broe³, Jean-Daniel Lalau^{4

5}

Affiliations

¹ Department of Clinical Pharmacology, Amiens University Hospital, Amiens, France.
² MP3CV laboratory, EA7517, University of Picardie Jules Verne, Amiens, France.
³ Laboratory of Pathophysiology, University of Antwerp, Wilrijk, Belgium.
⁴ Department of Endocrinology-Diabetology-Nutrition, Amiens University Hospital, Amiens, France.
⁵ PériTox UMR_I 01, University of Picardie Jules Verne, Amiens, France.

Editorial

Youssef Bennis et al. Crit Care Med. 2021.

. 2021 Apr 1;49(4):e461-e462.

doi: 10.1097/CCM.0000000000004901.

Youssef Bennis^{1

2}, Marc E De Broe³, Jean-Daniel Lalau^{4

5}

¹ Department of Clinical Pharmacology, Amiens University Hospital, Amiens, France.
² MP3CV laboratory, EA7517, University of Picardie Jules Verne, Amiens, France.
³ Laboratory of Pathophysiology, University of Antwerp, Wilrijk, Belgium.
⁴ Department of Endocrinology-Diabetology-Nutrition, Amiens University Hospital, Amiens, France.
⁵ PériTox UMR_I 01, University of Picardie Jules Verne, Amiens, France.

No abstract available

Conflict of interest statement

The authors have disclosed that they do not have any potential conflicts of interest.

A Study of Associations Between Plasma Metformin Concentration, Lactic Acidosis, and Mortality in an Emergency Hospitalization Context.
Bennis Y, Bodeau S, Batteux B, Gras-Champel V, Masmoudi K, Maizel J, De Broe ME, Lalau JD, Lemaire-Hurtel AS. Bennis Y, et al. Crit Care Med. 2020 Dec;48(12):e1194-e1202. doi: 10.1097/CCM.0000000000004589. Crit Care Med. 2020. PMID: 33003077
Therapeutic Strategy for Metformin-Associated Lactic Acidosis.
Izumida T, Imamura T. Izumida T, et al. Crit Care Med. 2021 Apr 1;49(4):e460-e461. doi: 10.1097/CCM.0000000000004805. Crit Care Med. 2021. PMID: 33731621 No abstract available.

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1. Seidowsky A, Nseir S, Houdret N, et al. Metformin-associated lactic acidosis: A prognostic and therapeutic study. Crit Care Med. 2009; 37:2191–2196
1. Posma RA, Hulman A, Thomsen RW, et al. Metformin use and early lactate levels in critically ill patients according to chronic and acute renal impairment. Crit Care. 2020; 24:585
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