Plasma Metformin Levels at Almost 24 Hours Would Help With the Delicate Decision to Start Renal Replacement Therapy: We Disagree as Lactate That Is More Widely and Early Available Should Be a Much Better Trigger to Start Renal Replacement Therapy!
- PMID: 33731623
- DOI: 10.1097/CCM.0000000000004860
Plasma Metformin Levels at Almost 24 Hours Would Help With the Delicate Decision to Start Renal Replacement Therapy: We Disagree as Lactate That Is More Widely and Early Available Should Be a Much Better Trigger to Start Renal Replacement Therapy!
Conflict of interest statement
The authors have disclosed that they do not have any potential conflicts of interest.
Comment in
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The authors reply.Crit Care Med. 2021 Apr 1;49(4):e464-e465. doi: 10.1097/CCM.0000000000004902. Crit Care Med. 2021. PMID: 33731624 No abstract available.
Comment on
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A Study of Associations Between Plasma Metformin Concentration, Lactic Acidosis, and Mortality in an Emergency Hospitalization Context.Crit Care Med. 2020 Dec;48(12):e1194-e1202. doi: 10.1097/CCM.0000000000004589. Crit Care Med. 2020. PMID: 33003077
References
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- Keller G, Cour M, Hernu R, et al. Management of metformin-associated lactic acidosis by continuous renal replacement therapy. PLoS One. 2011; 6:e23200
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- van Berlo-van de Laar IRF, Gedik A, van ‘t Riet E, et al. Identifying patients with metformin associated lactic acidosis in the emergency department. Int J Clin Pharm. 2020; 42:1286–1292